沈阳医学院学报2024,Vol.26Issue(5) :524-528.DOI:10.16753/j.cnki.1008-2344.2024.05.015

恶性肿瘤患者免疫治疗相关不良反应影响因素的研究进展

Research progress on influencing factors of immunotherapy-related adverse events in patients with malignant tumors

司亚杰 崔仁善 辛悦 胡雯雯
沈阳医学院学报2024,Vol.26Issue(5) :524-528.DOI:10.16753/j.cnki.1008-2344.2024.05.015

恶性肿瘤患者免疫治疗相关不良反应影响因素的研究进展

Research progress on influencing factors of immunotherapy-related adverse events in patients with malignant tumors

司亚杰 1崔仁善 2辛悦 1胡雯雯1
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作者信息

  • 1. 辽宁中医药大学护理学院,辽宁 沈阳 110847
  • 2. 嘉兴学院医学院护理系
  • 折叠

摘要

免疫检查点抑制剂(ICIs)是继传统手术、放化疗、靶向治疗后新兴的肿瘤治疗途径,在多种癌症中证实有明显疗效,但在接受治疗的过程中可能会诱发免疫治疗相关不良反应(irAEs),影响患者的生活质量,并可能导致治疗中断或停止.预防irAEs的关键在于医护人员的早期评估和识别,故本文对irAEs的临床表现及其影响因素展开综述,帮助早期识别高危人群,为临床护理工作提供借鉴.

Abstract

Immune checkpoint inhibitors(ICIs)are an emerging tumor treatment approach following traditional surgery,chemoradiotherapy and targeted therapy.They have proven to be effective in a variety of cancers.However,they may induce immune-related adverse events(irAEs)during treatment,which may affect patients'quality of life and lead to treatment interruption or cessation.The key to preventing irAEs is early evaluation and identification of medical staff.Therefore,this article reviews the clinical manifestations and influencing factors of irAEs to help the early identification of high-risk groups and provide reference for clinical nursing work.

关键词

恶性肿瘤/免疫检查点抑制剂/免疫治疗相关不良反应/影响因素

Key words

malignant tumor/immune checkpoint inhibitors/immune-related adverse events/influencing factors

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出版年

2024
沈阳医学院学报
沈阳医学院

沈阳医学院学报

影响因子:0.591
ISSN:1008-2344
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