摘要
目的 基于全膝关节磁共振成像评分(WORMS)分析3.0T磁共振(MR)影像对膝骨关节炎患者病情程度的应用价值.方法 所选取的96例膝骨关节炎患者均来源于濮阳市中医医院,选取时间为2023年3月至10月,进行回顾性分析,按照K-L分级标准将所有患者分为轻、重度组,另选择同期在本院进行健康体检的70名健康体检者,将其作为参照组.所有研究对象均接受3.0T MR影像检验,分别将轻度、重度组患者及参照组研究对象膝关节不同部位软骨T2值,西安大略和麦克马斯特大学骨关节炎指数(WOMAC)评分进行对比,采用Pearson相关性分析膝骨关节炎患者不同部位软骨T2值与WORMS评分的相关性.结果 重度组膝骨关节炎患者胫骨内侧区、股骨内侧区、胫骨外侧区、股骨外侧区及髌骨区软骨T2值均相较于轻度组患者更高,且轻度组患者胫骨内侧区、股骨内侧区、胫骨外侧区、股骨外侧区及髌骨区软骨T2值相较于参照组更高,差异有统计学意义(均P＜0.05);重度组膝骨关节炎患者疼痛、僵硬、关节功能及总分均相较于轻度组患者更高,且轻度组患者疼痛、僵硬、关节功能及总分相较于参照组更高,差异有统计学意义(均P＜0.05);Pearson相关性分析结果得出,膝骨关节炎患者股骨外侧区T2值与WORMS评分无相关性(r值=0.10,P＞0.05),而股骨内侧区、胫骨外侧区、胫骨内侧区及髌骨区T2值均与WORMS评分呈正相关(r值=0.80、0.86、0.71、0.61,均P＜0.05).结论 3.0T MR影像检查所获取的T2值与膝骨关节炎患者临床表现、软骨病变程度之间有着密不可分的关系,对膝骨关节炎患者应用3.0T MR影像检查可有效评定患者的软骨受损程度,从而为疾病的诊断、后续治疗方案的制定提供参考.
Abstract
Objective To analyze the application value of 3.0T MR imaging in patients with knee osteoarthritis based on total knee magnetic resonance imaging score.Methods Ninety-six patients with knee osteoarthritis were selected from Puyang Hospital of Traditional Chinese Medicine from March 2023 to October 2023 for retrospective analysis.According to the K-L grading criteria,all patients were divided into mild and severe groups,and 70 healthy patients who underwent physical examination in our hospital during the same period were selected as a reference group.All subjects were examined by 3.0T MR imaging.The T2 values of cartilage in different parts of the knee joint were compared between the mild and severe group and the reference group,and the Western Ontario and McMaster University Osteoarthritis Index(WOMAC)scores were compared between the mild and severe group and the reference group.Pearson correlation software was used to analyze the correlation between T2 values of cartilage in different parts of knee osteoarthritis patients and WORMS scores.Results Compared with the control group,the T2 values of the medial tibial region,medial femur region,lateral tibia region,lateral femur region,and patella region were all increased in patients with the severe knee joint,and the T2 values of the medial tibial region,medial femur region,lateral tibia region,lateral femur region,and patella region were increased in patients with mild knee joint.The difference was statistically significant(all P＜0.05).The pain,stiffness,joint function,and total score of the knee joint in the severe group were increased compared with those in the mild group,and the pain,stiffness,joint function and total score of the mild group were increased compared with the reference group,with statistical significance(all P＜0.05).The results of pearson correlation analysis showed that T2 value of the lateral femoral region in patients with knee osteoarthritis did not correlate with the WORMS score(r=0.10,P＞0.05).The T2 values of the medial femur,later-al tibia,medial tibia,and patella were positively correlated with WORMS scores(r=0.80,0.86,0.71,0.61,all P＜0.05).Conclusion The T2 value obtained by 3.0T MR imaging is closely related to the clinical manifestations and the de-gree of cartilage lesions in patients with knee osteoarthritis.The application of 3.0T MR imaging in patients with knee osteoarthritis can effectively assess the degree of cartilage damage in patients with knee osteoarthritis,to provide a reference for the diagnosis of the disease and the formulation of follow-up treatment.
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