Objective To analyze the anatomy and variation of the nasopalatine canal in normal adults in Xiamen by cone-beam CT.Methods The cone-beam CT image data of 102 patients who visited the Affliated Stomatology Hospital of Xiamen College from January 2020 to January 2023 were selected as the research objects,and the measurement indexes and standards in sagittal plane,coronal plane,and horizontal plane were formulated,and the patients were grouped according to age and gender.The relationship between age,sex,and each measurement index were analyzed.Results The median sagittal surface of nasopalatine canal was funnel-shaped in 35 cases(34.3%),cylindrical in 33 cases(32.4%),hourglass in 26 cases(25.5%),and banana in 8 cases(7.8%).Among the variations of nasopalatine canal coronal morphology,there were 44 cases with single tube,2 cases with double-parallel tubes,and 56 cases with Y-shaped tubes,among which 46 cases had 2 Stenson holes and 10 cases had 3 or more.There were 43 nasopalatine canals with only 1 Stenson foramen and incisal foramen,and 1 Stenson foramen with 3 incisal foramen.There were 48 cases with 2 stensons(46 cases with 1 incisor foramen and 2 cases with 2 incisor foramen).There were 10 cases with 3 or more Stenson foramen(3 Stenson foramen in 6 cases,4 Stenson foramen in 3 cases,5 Stenson foramen in 1 case),all of which had only 1 incisor foramen.According to gender,nasopalatine duct diameter D1,diameter D3,length L1,lower labial bone plate thickness W2,nasopalatine angle(A)were statistically significant between the two groups(P<0.05),but not statistically significant between the two groups(P>0.05).According to age group,the median diameter of nasopalatine canal D2,the diameter of inferior mouth D3,and the thickness of labial bone plate W1 and W2 were statistically significant among the three groups(P<0.05),but the remaining differences were not statistically significant(P>0.05).Conclusion The anatomical variation of the nasopalatine canal is common in normal adults in Xiamen.The diameter and length of the upper and lower mouth of the nasopalatine canal,the thickness of the lower labial bone plate,and the nasopalatine angle are correlated with sex,and the diameter of the middle and lower mouth of nasopalatine canal,the thickness of the upper and lower labial bone plate are correlated with age.