Objective To compare and analyze the characteristics of different molecular types of breast cancer liver metastases by multi-slice spiral CT(MSCT),and to understand the effect of MSCT in distinguishing different molecular types of breast cancer liver metastases.Methods A retrospective analysis of the data of patients with breast cancer liver metastases from December 2018 to August 2023 in the hospital was performed.MSCT scans were performed.According to different molecular types,they were divided into group A,group B,group C,and group D.The average number of metastases in the 4 groups,the proportion of single and multiple,the distribution of liver lobes,and the length,morphology,border,degree of enhancement,and density of metastases were compared.Results Comparison of the number of lesions:group A had the lowest number,followed by group B and group C,and group D had the highest number(P＜0.05).Single and multiple:the majority of patients in the four groups were multiple,with a higher proportion of multiple cases than single cases(P＜0.05).The proportion of multiple cases in the four groups was compared and there was no significant difference(P＞0.05).Liver lobe distribution:all four groups of patients were mainly affected by whole liver disease.Compared with the other three groups,the proportion of right lobe disease in group D was higher(P＜0.05).Size:the four groups were mainly composed of small metastases with a length diameter of≤2 cm,with a higher proportion than lesions with a length diameter of ≥ 2 cm(P＜0.05).The size of lesions in the four groups was compared and there was no significant difference(P＞0.05).Morphology:The four groups were mainly composed of circular or quasi-circular lesions,with a higher proportion than irregular lesions(P＜0.05).The morphology of the lesions in the four groups was compared(P＞0.05).Boundary:The proportion of lesions with clear and blurred boundaries in group A and group C was equivalent,and the comparison between the two groups was sig-nificant(P＞0.05).The proportion of blurred boundary lesions in group B was higher than that of clear lesions(P＜0.05).The proportion of well-defined lesions in group D was higher than that of blurred lesions(P＜0.05).The comparison between group B and group D,as well as between group B and group D and group A and group C,was significantly different(P＜0.05).Enhanced features:The four groups were mainly characterized by nodular enhancement,with a higher proportion than circular enhancement and atypical enhancement(P＜0.05).Density distribution:groups A and D are mainly low-density,with a higher proportion of low-density compared to isodensity,high-density,and cystic transformation(P＜0.05).The B and C groups were mainly low-density and isodensity,and there was no statistically significant difference in the proportion of low-density and isodensity(P＞0.05).The proportion of low-density in group A and group D was higher than that in group B and group C,while the proportion of isodensity was lower than that in group B and group C(P＜0.05).Conclusion Observation of liver metastases from different molecular types of breast cancer by MSCT can clarify the common characteristics and differences of the four types,especially in the distribution,boundary,and density of liver lobes of different types,which can provide a certain degree for clinical identification and precise treatment.guide.
关键词
乳腺肿瘤/体层摄影术,螺旋计算机/女性/分子分型/肝转移
Key words
Breast neoplasms/Tomography,spiral computed/Female/Molecular typing/Liver metastasis
维普
万方数据