Objective To explore the value of low-dose CT craniocerebral perfusion in the diagnosis of ischemic stroke,and to analyze the imaging features.Methods Forty-two patients with ischemic stroke admitted to the First Affiliated Hospital of Henan University of Science and Technology from January 2021 to June 2022 were retrospectively selected,and their clinical data were analyzed.All patients underwent conventional computed tomography(CT)plain scan and low-dose CT craniocerebral perfusion.The scanning parameters and radiation dose of the two methods were compared,as well as the parameters of the affected and contralateral perfusion of low-dose CT brain perfusion and the parameters of the ischemic penumbra and contralateral perfusion,and the typical cases were analyzed.Results The CT dose index volume(CTDIvol),dose-length product(DLP),and effective dose of low-dose CT were higher than that of plain CT.Under low-dose CT craniocerebral perfusion,the levels of cerebral blood flow(CBF)and cerebral blood volume(CBV)in all cerebral arteries and junction areas on the affected side were lower than those on the contralateral side,while the levels of time to peak(TTP)and mean transit time(MTT)were higher than those on the contralateral side.The level of CBF in the ischemic penumbra was lower than that on the opposite side,and the level of CBV,TTP,and MTT was higher than that on the opposite side,the difference was statistically significant(P＜0.05).Conclusion Low-dose CT craniocerebral perfusion can still achieve the expected diagnostic effect while reducing the radiation dose,and the parameters can be used as a reference to determine the affected side of ischemic stroke and ischemic penumbra,to provide more targeted diagnosis and treatmeni data,which has a high diagnostic value in clinical application and can be used as a reference basis for clinical diagnosis to guide clinical treatment.
关键词
卒中/体层摄影术,X线计算机/灌注成像/影像特征
Key words
Stroke/Tomography,X-ray computed/Perfusion imaging/Imaging features
维普
万方数据