Objective To explore the value of quantitative analysis of contrast-enhanced ultrasound in evaluating the degree of breast cancer invasion and resectable,in order to provide reference for clinical intervention.Methods A total of 118 breast cancer patients in our hospital from August 2020 to August 2022 were selected and underwent contrast-enhanced ultrasound examination after admission.Quantitative parameters of contrast-enhanced ultrasound,including time to peak(TTP),peak intensity(PI),and wash in slope,in patients with different degrees of breast cancer invasion were compared.The correlation between quantitative parameters of contrast-enhanced ultrasound(CEUS)and the degree of breast cancer invasion was analyzed,and the two groups were divided into surgical resection group(n=64)and non-surgical resection group(n=54)according to the actual clinical situation.The quantitative parameters of CEUS were compared between the two groups at admission,and the evaluation value of quantitative parameters of CEUS on the resectable breast cancer lesions was analyzed.Results TTP of patients with different degrees of invasive breast cancer was compared:invasive grade 1 group＞invasive grade 2 group＞invasive grade 3 group.PI and WIS were compared:infiltrating grade 1 group＜infiltrating grade 2 group＜infiltrating grade 3 group(P＜0.05).Correlation analysis showed that TTP was negatively correlated with the degree of breast cancer invasion,while PI and WIS were positively correlated with the degree of breast cancer invasion(P＜0.05).TTP,PI,and WIS in the surgical resection group were higher than in the non-surgical resection group(P＜0.05).Receiver operator characteristic curve(ROC)analysis showed that the area under the curve(AUC)of the combined evaluation of TTP,PI,and WIS for breast cancer resection was 0.927,greater than that of a single parameter.The risk of inoperable resection in low TTP,PI,and WIS groups was 2.803,0.580,and 0.444 times of that in high TTP,PI,and WIS groups,respectively(P＜0.05).Conclusion Quantitative analysis of contrast-enhanced ultrasound can be used to evaluate the degree of breast cancer invasion,provide evidence for clinical evaluation of resectable,and make follow-up treatment.
维普
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