Progress in targeted complement therapy for IgA nephropathy
More and more evidences have demonstrated that the activation of complement system plays a critical role in the pathogenesis and progression of IgA nephropathy(IgAN).In recent years,the emerging drugs targeting complement components have provided new measures for IgAN.Drugs targeting complement components such as complement C3,B factor,D factor,complement C5 and C5a receptor,etc.,have entered clinical trials for the treatment of IgAN.This article reviews the progression of targeted complement therapy for IgAN.
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