结核性脑积水患者的侧脑室和腰大池脑脊液参数相关性分析
Correlation analysis of cerebrospinal fluid parameters between lateral ventricle and lumbar cisterna in patients with tuberculosis hydrocephalus
孙久君 1殷成2
作者信息
- 1. 四川省达州市中心医院神经外科,四川 达州 635000
- 2. 四川省医学科学院·四川省人民医院神经外科,四川 成都 610072
- 折叠
摘要
目的 探讨在脑室腹腔分流术治疗结核性脑积水时,使用侧脑室脑脊液和使用腰大池脑脊液化验结果作为分流参考指标的差异.方法 回顾性纳入28 例结核性脑积水患者.在进行脑室腹腔分流术之前,分别从腰大池和侧脑室取脑脊液,送常规与生化检测.对上述来源两个不同部位的脑脊液进行参数分析,并随访患者手术疗效.结果 腰大池有核细胞、葡萄糖、氯化物、蛋白质含量与侧脑室这些指标有明显相关性(P<0.05);腰大池脑脊液有核细胞和蛋白水平明显高于侧脑室(P<0.05).后期随访过程中,除1 例失去联系,其余患者手术效果良好.结论 由于侧脑室脑脊液与腰大池脑脊液存在明显差异,脑室腹腔分流术应取侧脑室脑脊液作为分流的临床参考指标.
Abstract
Objective To explore the differences in use of parameters of cerebrospinal fluid(CSF)in lateral ventricle and in lumbar cistern as a reference for ventriculoperitoneal shunt(VPS)in patients with tuberculosis hydrocephalus(TBH).Methods In this retrospective study,28 TBH patients who underwent VPS were involved.The CSF was collected from lumbar cistern and lateral ventricle before VPS,respectively.The collected CSF was detected by the routine and biochemical testing.Parametric analysis of CSF from the above two different parts was preformed.The surgical efficacy was followed up.Results There was obvious relationship between the level of nucleated cells,glucose,chlorine and protein in lumbar cistern and that in lateral ventricle(P<0.05).The levels of nucleated cells and proteins in CSF of lumbar cistern were significantly higher than those in lateral ventricle(P<0.05).During the later follow-up,except for one patient who lost contact,all patients had good surgical results.Conclusions There is obvious difference of CSF between lateral ventricle and lumbar cistern.It should refer to the parameters of lateral ventricle CSF as a clinical indicator of VPS.
关键词
结核性脑积水/脑脊液/腰大池/侧脑室/脑室腹腔分流术Key words
Tuberculosis hydrocephalus/Cerebrospinal fluid/Lateral ventricle/Lumbar cistern/Ventriculoperitoneal shun-ting引用本文复制引用
基金项目
国家自然科学基金面上项目(82071318)
出版年
2024
NETL
NSTL
万方数据