Research progress in serum markers of progressive pulmonary fibrosis
In addition to idiopathic pulmonary fibrosis,the degree of pulmonary fibrosis of some interstitial lung diseases continues to worsen after active treatment.This leads to progressive reduction in lung function and increased risk of early death.This kind of disease with progressive pulmonary fibrosis phenotype is referred to as a general name of progressive fibrotic interstitial lung disease.The etiology of pulmonary fibrosis is complex.Their diagnosis and treatment are difficult.In recent years,a lot of exploration has been conducted on various biomarkers related to pulmonary fibrosis.It has been found that these markers have certain clinical value in the diagnosis,disease evaluation and disease monitoring.This article summarizes and analyzes the serological markers related to pro-gressive pulmonary fibrosis in order to improve the further understanding and clinical application of these markers.