脑血容量指数预测急性缺血性卒中患者血管内治疗远期预后的价值分析
Value analysis of cerebral blood volume index in the prediction of the long-term prognosis of endovascular therapy in patients with acute ischemic stroke
张琦 1杨树 2成旭东 3黎炳护 2余能伟2
作者信息
- 1. 电子科技大学,四川 成都 610054;四川省医学科学院·四川省人民医院神经内科,四川 成都 610072
- 2. 四川省医学科学院·四川省人民医院神经内科,四川 成都 610072
- 3. 四川省医学科学院·四川省人民医院神经内科,四川 成都 610072;西南医科大学,四川 泸州 646000
- 折叠
摘要
目的 探讨CT灌注指数与急性缺血性卒中(AIS)患者血管内治疗(EVT)远期预后的相关性.方法 纳入 64例诊断AIS且经EVT的患者并进行1 年随访.主要结局指标包括术后1 年改良Rankin量表(mRS)评分0～2 分(良好预后).所有患者根据低灌注强度比(HIR)(<0.3 vs≥0.3)和脑血容量(CBV)指数(>0.7 vs≤0.7)进行分组,将组间临床资料及术后1 年mRS评分进行比较;通过Logistic回归分析术后1 年良好预后的影响因素.结果 61 例患者完成随访,其中术后1 年达到良好预后的有34 例(55.7%).高CBV组良好预后率明显高于低CBV组(76.9%vs 40%),低HIR组良好预后率明显高于高HIR组(73.9%vs 44.7%)(P<0.05).CBV指数是术后1 年良好预后的保护因素(P=0.046).结论 CBV指数可预测AIS患者EVT远期预后情况,有望为患者EVT提供临床依据.
Abstract
Objective To the explore the relationship between CT perfusion index and good long-term prognosis in acute ischaemic stroke(AIS)patients receiving endovascular therapy(EVT).Methods A total of 64 patients diagnosed with AIS and treated with EVT were included and followed up for 1 year.The main outcome measures included 1-year good prognosis was defined as modified Rankin Scale(mRS)score 0-2.All patients were grouped based on the hypoperfusion intensity ratio(HIR;<0.3 vs.≥0.3)and cerebral brain volume(CBV)index(>0.7 vs.≤0.7).The mRS score and other clinical data of the groups were compared.Logistic regression analysis was used to analyze the factors affecting the good prognosis at 1 year after EVT.Results Sixty-one patients were eventually completed this study,and 34(55.7%)patients achieved mRS 0-2 after 1 year of surgery.The 1-year good prognosis rate was significantly higher in the high CBV group than in the low CBV group(76.9%vs.40%,P<0.05).The good prognosis rate was significantly higher in the low HIR group than in the high HIR group(73.9%vs.44.7%,P<0.05).CBV index is a protective factor for the good prognosis after 1 year of EVT(P = 0.046).Conclusions CBV index can predict the long-term prognosis of AIS patients treated with EVT.It provides the clinical evidence for EVT in the AIS patients.
关键词
急性缺血性卒中/血管内治疗/CT灌注/脑血容量指数/低灌注强度比Key words
Acute ischemic stroke/Endovascular therapy/CT perfusion/Cerebral brain volume index/Hypoperfusion引用本文复制引用
基金项目
四川省科技厅科研基金资助项目(2021YFS0074)
成都市科技计划项目(2019-YF09-00142-SN)
出版年
2024
NETL
NSTL
万方数据