Value analysis of cerebral blood volume index in the prediction of the long-term prognosis of endovascular therapy in patients with acute ischemic stroke
Objective To the explore the relationship between CT perfusion index and good long-term prognosis in acute ischaemic stroke(AIS)patients receiving endovascular therapy(EVT).Methods A total of 64 patients diagnosed with AIS and treated with EVT were included and followed up for 1 year.The main outcome measures included 1-year good prognosis was defined as modified Rankin Scale(mRS)score 0-2.All patients were grouped based on the hypoperfusion intensity ratio(HIR;<0.3 vs.≥0.3)and cerebral brain volume(CBV)index(>0.7 vs.≤0.7).The mRS score and other clinical data of the groups were compared.Logistic regression analysis was used to analyze the factors affecting the good prognosis at 1 year after EVT.Results Sixty-one patients were eventually completed this study,and 34(55.7%)patients achieved mRS 0-2 after 1 year of surgery.The 1-year good prognosis rate was significantly higher in the high CBV group than in the low CBV group(76.9%vs.40%,P<0.05).The good prognosis rate was significantly higher in the low HIR group than in the high HIR group(73.9%vs.44.7%,P<0.05).CBV index is a protective factor for the good prognosis after 1 year of EVT(P = 0.046).Conclusions CBV index can predict the long-term prognosis of AIS patients treated with EVT.It provides the clinical evidence for EVT in the AIS patients.