首页|不同颅骨修补时机对创伤性颅脑重型损伤患者脑血流动力学、神经功能及预后的影响

不同颅骨修补时机对创伤性颅脑重型损伤患者脑血流动力学、神经功能及预后的影响

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目的 研究不同颅骨修补时机对创伤性颅脑重型损伤(STBI)患者脑血流动力学、神经功能及预后的影响.方法 选择我院2020 年7 月至2022 年6 月在我院行颅骨修补的STBI患者90 例,随机数字表法分为早期组(n=45)与对照组(n=45),两组分别于去骨瓣减压术(DC)后4~6 周、3~6 个月行颅骨修补术.观察两组术前、术后 3 个月神经功能,精神状况、日常生活能力;脑血流动力学指标:大脑前动脉(ACA)、中动脉(MCA)及后动脉(PCA)血流速度;以及并发症.结果 术后3 个月,早期组mRS评分、NIHSS评分及并发症发生率均低于对照组,ACA、MCA及PCA血流速度及MMSE评分、BI评分均高于对照组(P<0.05).结论 相较于DC术后3~6 个月颅骨修补,DC术后4~6 周行颅骨修补可有效恢复STBI患者神经功能,改善脑血流动力学,使其精神状况得到显著提振,日常生活能力得到显著提高,且安全性较高.
The effects of cranioplasty different timing on cerebral hemodynamics,neurological function and prognosis of patients with severe traumatic brain injury
Objective To investigate the effects of cranioplasty different timing on cerebral hemodynamics,neurological function and prognosis of patients with severe traumatic brain injury(STBI).Methods Ninety STBI patients who underwent skull repair in our hospital from July 2020 to June 2022 were selected.The patients were divided into an early group and a control group by using random number table method,45 in each group.Cranioplasty was performed in the early group and the control group within 4-6 weeks and 3-6 months after decompressive craniectomy(DC),respectively.The neurological function,mental state,ability of daily living,cerebral hemodynamic indexes such as blood flow velocity of anterior cerebral artery(ACA),middle artery(MCA)and posterior artery(PCA)as well as complications of the patients in two groups was observed before and after 3 months of operation.Results After 3 months of operation,mRS score,NIHSS score and complication rate in the early group were lower than those in the control group.The blood flow velocity of ACA,MCA and PCA,MMSE score and BI score in the early group were higher than those in the control group(P<0.05).Conclusions Compared with skull repair within 3 to 6 months after DC surgery,skull repair performed within 4 to 6 weeks after DC surgery can effectively restore the nerve function of STBI patients,improve the cerebral hemodynamics,significantly boost their mental status,and significantly improve their daily living ability.Its safety is also high.

Different timingCranioplastySevere traumatic brain injuryNeurological functionCerebral hemodynamicsPrognosis

尚彬、陈华轩、罗波、张渊、云德波

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四川省南充市中心医院神经外科,四川 南充 637000

不同时机 颅骨修补术 创伤性颅脑重型损伤 神经功能 脑血流动力学 预后

南充市科技局科技计划项目

18SXHZ0331

2024

实用医院临床杂志
四川省医学科学院 四川省人民医院

实用医院临床杂志

CSTPCD
影响因子:1.179
ISSN:1672-6170
年,卷(期):2024.21(2)
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