Clinical observation of lung rehabilitation combined with non-invasive ventilation in the treatment of chronic obstructive pulmonary disease with respiratory failure
Objective To investigate the effects of lung rehabilitation combined with non-invasive ventilation on clinical efficacy,lung function and blood gas analysis in patients with chronic obstructive pulmonary disease(COPD)complicated with respiratory failure.Methods One hundred and fifty-one patients with COPD combined with respiratory failure admitted to our hospital from March 2020 to April 2023 were selected.The patients were divided into a control group(n=74)and an observation group(n=77)according to different treatment plans.The control group was treated with non-invasive ventilation therapy and the observation group was treated with pulmonary rehabilitation+non-invasive ventilation therapy.The clinical efficacy,pulmonary function such as forced expiratory volume in the first second(FEV1),maximum expiratory flow(PEF)and forced vital capacity(FVC),blood gas analysis such as partial pressure of arterial oxygen(PaO2)and partial pressure of arterial carbon dioxide(PaCO2)and treatment situation were compared between the two groups.Results The total effective rate of the observation group was higher than that of the control group(P＜0.05).After 28 days of treatment,the lung function indexes and the improvement degree of blood gas analysis indexes of the observation group were higher than those of the control group(P＜0.05).There was no difference in in-hospital mortality within 30 days after treatment between the two groups(P＞0.05).The ICU stay time and tracheal intubation rate in the obser-vation group were shorter than those in the control group(P＜0.05).Conclusions Pulmonary rehabilitation combined with non-invasive ventilation has a better therapeutic effect in the treatment of COPD patients with respiratory failure.It can effectively improve the pulmonary function and blood gas analysis indexes of COPD patients with respiratory failure.
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