首页|脊柱微创通道镜系统辅助椎间孔腰椎椎体间融合术治疗腰椎退行性疾病的临床效果观察

脊柱微创通道镜系统辅助椎间孔腰椎椎体间融合术治疗腰椎退行性疾病的临床效果观察

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目的 探讨脊柱微创通道镜系统辅助椎间孔腰椎椎体间融合术(TLIF)对腰椎退行性疾病患者脊髓功能及血清P物质(SP)、前列腺素E2(PGE2)水平的影响.方法 选取51 例腰椎退行性疾病患者,按照入院次序单双号法分为A组(n=25)及B组(n=26).A组行脊柱微创通道镜系统辅助TLIF术治疗,B组行常规TLIF术治疗.比较两组手术指标,腰腿部疼痛与功能障碍状况,脊髓功能,血清P物质(SP)、前列腺素E2(PGE2)水平.结果 A组术中失血量、术后引流量均少于B组,下床活动时间短于B组(P＜0.05);术后4 周两组腰腿部视觉模拟评分法(VAS)与Oswestry障碍指数(ODI)评分均较术前均明显改善(P＜0.05);术后7d两组各项脊髓功能指标较术前均明显改善,且A组改善幅度优于B组(P＜0.05);术后 3dA组血清SP水平高于B组,而血清PGE2 水平低于B组(P＜0.05).结论 脊柱微创通道镜系统辅助TLIF术可显著改善腰椎退行性疾病患者脊髓功能以及疼痛介质水平.
Observation on the clinical effect of intervertebral foramen and lumbar interbody fusion assistedby spinal minimally invasive channel endoscopy system in the treatment of lumbar de-generative diseases
Objective To investigate the effects of transforaminal lumbar interbody fusion(TLIF)assisted by spinal minimally invasive channel mirror system on spinal cord function as well as serum levels of substance P(SP)and prostaglandin E2(PGE2)in patients with lumbar degenerative diseases.Methods Fifty-one patients with lumbar degenerative diseases were selected.They were divided into group A(n=25)and B(n=26)according to the odd-even number method of admission order.The group B was treated with conventional TLIF,and the group A was treated with TLIF assisted with spinal minimally invasive channel mirror system.The surgical indexes,lumbar and leg pain and dysfunction,spinal cord function,serum SP and PGE2 levels were compared between the two groups.Results The intraoperative blood loss and postoperative drainage volume of the group A were less than those of the group B,and the time of getting out of bed of the group A was shorter than that of the B group(P＜0.05).Lumbar Visual Ana-logue Scale(VAS)and Oswestry Disability Index(ODI)scores of both groups were significantly improved after 4 weeks of surgery(P＜0.05).The indexes of spinal cord function in both groups were significantly improved after 7 days of operation,and the improvement in the group A was better than that in the group B(all P＜0.05).The serum SP level of the group A was higher than that of the group B,but the serum PGE2 level of the group A was lower than that of the group B(all P＜0.05).Conclusions TLIF assisted by minimally invasive spinal channel endoscopic system can significantly improve the spinal cord function and pain mediators in patients with lumbar degenerative diseases.

Transforaminal lumbar interbody fusionSpinal minimally invasive access mirror systemForaminal lumbar interbody fusionSpinal cord functionSubstance PProstaglandin E2

王巧迪、李越、肖清清、刘道德

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成都体育学院运动医学与健康学院,四川 成都 610041

四川省骨科医院颈肩腰腿痛1 科,四川 成都 610041

成都体育学院附属体育医院脊柱病科,四川 成都 610041

腰椎退行性疾病 脊柱微创通道镜系统 椎间孔腰椎椎体间融合术 脊髓功能 P物质 前列腺素E2

四川省干部保健科研项目

川干研2022-601

2024

实用医院临床杂志
四川省医学科学院 四川省人民医院

实用医院临床杂志

CSTPCD
影响因子：1.179
ISSN：1672-6170
年,卷(期)：2024.21(3)
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