首页|鼻肠管管饲法在晚期帕金森病患者肠内营养支持治疗中的应用研究

鼻肠管管饲法在晚期帕金森病患者肠内营养支持治疗中的应用研究

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目的 探讨保留鼻肠管进行肠内营养支持治疗对晚期帕金森病患者营养状况及并发症的影响.方法 2020年2月至2023年3月某三甲医院及医联体医院收治的 32 例晚期帕金森病患者,采用留置鼻肠管管饲法进行肠内营养支持治疗,二周后,观察血红蛋白、总蛋白、白蛋白、球蛋白实验室检查指标、肌张力评分以及胃食道返流、误吸和吸入性肺炎并发症发生例次,运用SF-36 评分评估患者生活质量,比较干预前后上述指标的变化情况.结果 留置鼻肠管管饲法行肠内营养的患者血清血红蛋白、总蛋白、白蛋白水平较前显著升高(P<0.05),球蛋白有上升但较干预前差异无统计学意义(P>0.05);干预后肌张力降低,胃食道返流、误吸和吸入性肺炎发生例数明显降低(P<0.05),生活质量评分差异无统计学意义(P>0.05).结论 采用鼻肠管管饲法对晚期帕金森病患者进行肠内营养支持治疗,患者营养状况有明显改善,能减少因进食引发的并发症发生,有临床应用价值.
Application of naso-intestinal tube feeding in enteral nutrition support for patients with advanced Parkinson's disease
Objective To explore the effect of enteral nutrition support with naso-intestinal tube on nutritional status and com-plications in patients with advanced Parkinson's disease.Methods Thirty-two patients with advanced Parkinson's disease from February,2020 to January,2023 were selected.The patients were treated with enteral nutrition support through indwelling naso-intestinal tube.After 2 weeks,the laboratory test indicators such as hemoglobin,total protein,albumin and globulin were observed.The muscle tone score and the incidence of gastroesophageal reflux,aspiration and aspiration pneumonia complications were recorded.SF-36 score was conducted to evaluate the quality of life of patients.The changes of above indicators were compared before and after in-tervention.Results The levels of hemoglobin,total protein and albumin after intervention were significantly higher than those before intervention(P<0.05).The levels of globulins were increased,but there was no significant difference between before and after intervention(P>0.05).After intervention,the muscle tone was decreased and the incidence of aspiration and aspiration pneumonia complications was significantly decreased(P<0.05).There was no significant difference in scores of the quality of life before and after intervention(P>0.05).Conclusions Naso-enteral tube feeding is used to provide enteral nutrition support treatment for patients with advanced Parkinson's disease.The nutritional status of the patients has been significantly improved,and complications caused by eating can be reduced.It has a clinical application value.

Naso-intestinal tubeEnteral NutritionParkinson's diseaseComplications

蒋蓉、余艳、张丁丁、吴红英、李梅、刘艳

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四川省医学科学院·四川省人民医院(电子科技大学附属医院) 老年医学中心,四川 成都 610072

四川省医学科学院·四川省人民医院(电子科技大学附属医院) 日间手术病房,四川 成都 610072

四川省医学科学院·四川省人民医院(电子科技大学附属医院) 医学遗传中心,四川 成都 610072

四川省医学科学院·四川省人民医院(电子科技大学附属医院) 营养科,四川 成都 610072

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鼻肠管 肠内营养 帕金森病 并发症

四川省干部保健科研课题

川干研2019-223

2024

实用医院临床杂志
四川省医学科学院 四川省人民医院

实用医院临床杂志

CSTPCD
影响因子:1.179
ISSN:1672-6170
年,卷(期):2024.21(3)
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