Research progress in early diagnosis of sepsis based on biomarkers and microfluidic technology
Sepsis has become a major problem in the global public health.Due to its initial signs and symptoms are non-specific and there is no sufficiently sensitive or specific diagnostic scoring systems and biomarkers,patients often fail to receive timely diagnosis and treatment.This leads to extremely high mortality.Therefore,early recognition of sepsis and timely intervention are particularly important.Novel sepsis-related molecules and biomarkers are also worthy of further research.This article will review the main diagnostic methods of sepsis in detail.These include clinical assessment,biomarkers and emerging diagnostic technologies.Our aim is to provide a comprehensive reference for clinical workers.