Comparison of the clinical effects of the high-intensity focused ultrasound ablation and uterine artery embolization in the treatment of uterine fibroid
Objective To compare the efficacy of high-intensity focused ultrasound(HIFU)and uterine artery embolization(UAE)in the treatment of uterine fibroid(UF).Methods Eighty-six patients with UF undergoing interventional therapy from January 2020 to June 2022 were collected.The patients were divided into a HIFU group(n=44)and an UAE group(n=42)according to treatment methods.Stress response,endometrial receptivity,sex hormone level,complication and recurrence rate were compared between the two groups.Results After 3 days of operation,serum norepinephrine(NE)and malondialdehyde(MDA)were lower and superoxide dismutase(SOD)was higher in the HIFU group than those in the UAE group(P＜0.05).After one month of operation,endometrial thickness was higher and endometrial artery blood flow pulsatility index and endometrial artery blood flow resistance index were lower in the HIFU group than those in the UAE group(P＜0.05).After 3 months of operation,serum E2 was lower and FSH and LH in the HIFU group were higher than those in the UAE group(P＜0.05).Follow-up 12 months,complication in the HIFU group was 4.09％that was lower than 57.14％in the UAE group(x2=4.607,P＜0.05).Recurrence rate in the HIFU group was 22.73％that was higher than 7.14％in the UAE group(x=4.067,P＜0.05).Conclusions HIFU therapy can alleviate the stress response of UF patients,improve the endometrial receptivity and sex hormone level,and reduce the postoperative complications.However,it has a risk of inducing postoperative recurrence.
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