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布托啡诺对胸腔镜手术后肺部并发症的影响

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目的 观察布托啡诺对胸腔镜手术患者术后7天内肺部并发症发生率的影响.方法 选择择期拟行胸腔镜手术的患者,采用随机数字表法分为布托啡诺组(B组)和对照组(C组).B组于麻醉诱导时静脉注射布托啡诺10 μg/kg,随后持续泵注布托啡诺10 μg/(kg·h)至手术结束;C组给予等体积的生理盐水.比较两组术后7天肺部并发症类型(包括肺炎、肺不张、胸腔积液、气胸、支气管痉挛、吸入性肺损伤)、术后住院天数、其他并发症和视觉模拟量表(VAS)疼痛评分.结果 术后7天B组发生肺部并发症41例,低于C组的62例(P<0.05);B组术后两种及以上类型的肺部并发症发生率及术后住院天数低于C组,术后头晕发生率高于C组(P<0.05),两组其他术后并发症发生率比较,差异无统计学意义(P>0.05).在术后24 h的静息状态下,B组的VAS疼痛评分低于C组,差异有统计学意义(P<0.05).结论 布托啡诺能够降低胸腔镜手术患者7天内肺部并发症的发生率,缩短术后住院天数.
The effect of butorphanol on pulmonary complications after thoracoscopic surgery
Objective To observe the effect of butorphanol on the incidence of postoperative pulmonary complications(PPCs)within 7 days after thoracoscopic surgery.Methods Patients who plan to undergo thoracoscopic surgery on a scheduled date were divided into a butorphanol group(group B)and a control group(group C)using a random number table method.The group B received intravenous injection of butorphanol 10μg/kg during anesthesia induction,followed by continuous infusion of butorphanol 10 μg/(kg·h)until the end of the operation.The group C was given an equal volume of normal saline.The types of postoperative pulmonary complications such as pneumonia,atelectasis,pleural effusion,pneumothorax,bronchospasm and inhalation lung injury within 7 days after operation,postoperative hospital stay,other complications and Visual Analogue Scale(VAS)pain scores were compared between the two groups.Results Within 7 days after operation,41 cases of PPCs occurred in the group B,that was lower than 62 in the group C(P<0.05).The incidence rate of two or more types of PPCs and postoperative hospitalization days in the group B were lower or shorter than those in the group C and the incidence of postoperative dizziness in the group B was higher than that in the group C(P<0.05).There was no difference in the incidence of other PPCs between the two groups(P>0.05).Within 24 hours after surgery,the VAS pain score in the group B was lower than that in the group C(P<0.05).Conclusions Butorphanol can reduce the incidence of pulmonary complications within 7 days and shorten the postoperative hospital stay in patients undergoing thoracoscopic surgery.

ButorphanolThoracoscopic surgeryPostoperative pulmonary complications

周青山、张玉、刘利、曾思、徐广民

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电子科技大学医学院,四川成都 610002

成都中医药大学医学与生命科学学院,四川 成都 610072

四川省医学科学院·四川省人民医院(电子科技大学附属医院)麻醉科,四川 成都 610072

布托啡诺 胸腔镜手术 术后肺部并发症

四川省医学会基金临床研究及转化基金四川省科技厅重点研发项目第二版

S200252021LY182022YFS0301

2024

实用医院临床杂志
四川省医学科学院 四川省人民医院

实用医院临床杂志

CSTPCD
影响因子:1.179
ISSN:1672-6170
年,卷(期):2024.21(4)
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