Observation on the clinical efficacy of cefuroxime and amoxicillin clavulanate potassium combined with budesonide in the treatment of pediatric pneumonia
Objective To explore the clinical efficacy of amoxicillin clavulanate potassium and cefuroxime combined with budesonide in the treatment of pediatric pneumonia.Methods A total of 100 children with pneumonia admitted to our hospital from January 2022 to April 2023 were selected.The sick children were divided into an experimental group(n=52)and a control group(n=48)according to different treatment regimen.The experimental group was treated with amoxicillin clavulanate potassium combined with budesonide.The control group was treated with cefuroxime combined with budesonide.The clinical therapeutic effect,levels of C-reactive protein(CRP),tumor necrosis factor-α(TNF-α),interleukin-6(IL-6)and other inflammatory factors before and after treatment were compared between the two groups.Respiratory symptoms and imaging recovery,nausea,loss of appetite and rash after treatment were also compared between the two groups.Results After treatment,there was no significant difference in curative effect between the two groups(P＞0.05).After treatment,the levels of CRP,TNF-α and IL-6 in both groups were improved,and the levels in the control group were higher than those in the experimental group(P＜0.05).After treatment,the time of respiratory symptoms and imaging recovery in the experimental group were shorter than that of the control group(P＜0.05).There was no significant difference in the incidence of nausea,loss of appetite and rash between the two groups after treatment(P＞0.05).Conclusions When amoxicillin clavulanate potassium and cefuroxime combined with budesonide respectively to treat the pediatric pneumonia,amoxicillin clavulanate potassium is effective and safe.It is more suitable for pediatric pneumonia patients.This can provide effective guidance for the clinical treatment of pediatric pneumonia.
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维普
