The effect of thoracic paravertebral block combined with intravenous and inhalation general anesthesia on postoperative analgesia and cognitive function in elderly patients undergoing laparoscopic cholecystectomy
Objective To explore the effect of thoracic paravertebral block(TPVB)combined with intravenous and inhalation general anesthesia on postoperative analgesia and cognitive function in elderly patients undergoing laparoscopic cholecystectomy(LC).Methods Fifty-eight elderly patients underwent LC in our hospital were selected.The patients were divided into a combination group and a general anesthesia group by the random number table method,29 in each group.The general anesthesia group was given intravenous and inhalation general anesthesia.The combination group was given TPVB combined with intravenous and inhalation general anesthesia.The quality of recovery,remedial analgesia status within 48 h after surgery,pain score within 24 h after surgery,and cognitive function recovery within 3 days after surgery were compared between the two groups.Results The recovery quality in the combination group was higher than that in the general anesthesia group(P<0.05).The number of effective patient controlled intravenous analgesia(PCIA)compressions after surgery in the combination group was significantly less than that in the general anesthesia group(P<0.05).There was no significant difference in the rate of remedial analgesia after surgery(P>0.05).The VAS score in the combination group within 24 h after surgery was significantly lower compared to the general anesthesia group(P<0.05).The incidence of cognitive dysfunction 1 day after surgery in the combined group was significantly lower than that in the general anesthesia group(P<0.05).Conclusions TPVB combined with intravenous and inhalation general anesthesia in elderly LC patients can help to improve the recovery quality,and assist the postoperative analgesia.It also speeds up the recovery of cognitive function of the patients.It is worthy of recommendation.
Nerve blockGeneral anesthesiaRemedial analgesiaCognitive function