首页|基于肝脾相关理论探讨胆汁酸代谢异常对代谢相关脂肪性肝病的影响

基于肝脾相关理论探讨胆汁酸代谢异常对代谢相关脂肪性肝病的影响

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代谢相关脂肪性肝病已成为临床常见慢性肝病,国内外研究表明,胆汁酸已被确定为参与糖脂代谢的重要信号分子,胆汁酸代谢异常和肠道菌群紊乱与非酒精性脂肪肝的疾病严重程度密切相关,这种病理机制与传统医学中肝脾损伤在代谢相关脂肪性肝病中的致病机制相符合.文章结合肝脾相关理论探讨胆汁酸代谢异常对代谢相关脂肪性肝病的影响,以期为中西医结合防治代谢相关脂肪性肝病提供新的参考.
Exploring Impact of Abnormal Bile Acid Metabolism on Metabolism-Related Fatty Liver Disease Based on Liver-Spleen Related Theory
Metabolic fatty liver disease has become a common chronic liver disease.Domestic and international studies have shown that bile acid has been identified as an important signaling molecule involved in glycolipid metabolism,and abnormal bile acid metabolism and intestinal flora disorders are closely related to the disease severity of non-alcoholic fatty liver disease.Therefore,this paper discussed the effects of abnormal bile acid metabolism on metabolism-related fatty liver disease in the con-text of liver and spleen-related theories and provided a new reference for the prevention and treatment of metabolism-related fatty liver disease by combining traditional Chinese and western medicine.

liver and spleen being relatedmetabolism-related fatty liver diseasebile acid metabolismintestinal flora

徐翠瑜、张明香

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辽宁中医药大学,辽宁沈阳 110847

沈阳市第九人民医院,辽宁沈阳 110024

肝脾相关 代谢相关脂肪性肝病 胆汁酸代谢 肠道菌群

国家自然科学基金青年科学基金沈阳市科技计划公共卫生研发专项

81703933沈科发[2022]4

2024

实用中医内科杂志
辽宁省中医药学会,中华中医药学会,辽宁省中医药研究院

实用中医内科杂志

影响因子:0.421
ISSN:1671-7813
年,卷(期):2024.38(1)
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