Clinical Observation on the Clinical Effect of Duhuo Jisheng Decoction(独活寄生汤)Combined with External Washing of Traditional Chinese Medicine in the Treatment of Deficiency of Liver And Kidney of Rheumatoid Arthritis
Objective To investigate the clinical effect of Duhuo Jisheng Decoction(独活寄生汤)orally combined with exter-nal washing of traditional Chinese medicine on rheumatoid arthritis with liver and kidney deficiency syndrome.Methods A total of 86 patients with rheumatoid arthritis syndrome of liver and kidney deficiency admitted to Xuzhou Affiliated Hospital of Nanjing U-niversity of Chinese Medicine,from December 2019 to December 2022 were selected and divided into observation group and con-trol group according to random number table method,with 43 cases in each group.The observation group was treated with Metho-trexate(MTX),Hydroxychloroquine(HCQ),Duhuo Jisheng Decoction and Traditional Chinese medicine external washing,and the control group was treated with Methotrexate and Hydroxychloroquine.Clinical efficacy,simplified disease activity index(SDAI),clinical disease activity index(CDAI),erythrocyte sedimentation rate(ESR),C-reactive protein(CRP)and interleu-kin-6(IL-6)were compared between the two groups.Results The effective rate in the observation group was higher(P<0.05).After treatment,CD AI score and SDAI score of two groups were decreased compared with that before treatment(P<0.05),and the decrease level of observation group was higher than control group(P<0.05).After treatment,the levels of ESR,CRP and IL-6 in both groups were lower than those before treatment(P<0.05),and those in the observation group were lower than those in the control group(P<0.05).Conclusion Duhuo Jisheng Decoction combined with traditional Chinese medicine for external washing in the treatment of rheumatoid arthritis patients with liver and kidney deficiency syndrome can improve clinical symptoms,effective,reduce the release of inflammatory factors,safe and reliable.
Duhuo Jisheng Decoction(独活寄生汤)external washing of traditional Chinese medicinerheumatoid arthri-tisdeficiency syndrome of liver and kidneypromote blood circulation and collaterals