Effect of Jiawei Wenjing Decoction(温经汤)on Primary Dysmenorrhea of Cold Coagulation and Blood Stasis Type and Its Influence on Uterine Artery Hemodynamics
Objective To explore the effect of Jiawei Wenjing Decoction(温经汤)on primary dysmenorrhea of cold coagula-tion and blood stasis type and its influence on uterine artery hemodynamics.Methods 120 patients with primary dysmenorrhea who were treated in Puyang Maternal and Child Health Hospital from January 2021 to December 2022 were randomLy divided into observation group and control group,with 60 patients in each group.The control group was given ibuprofen sustained-release capsule orally,and the observation group was given Jiawei Wenjing Decoction.Observe and compare the TCM symptom score and curative effect of the two groups before and after the intervention;Peripheral blood pain mediator(prostaglandin F2 α[PGF2 α],β-Endorphin[β-EP],5-hydroxytryptamine[5-HT],prostaglandin E2[PGE2])levels;Uterine artery hemo-dynamic indexes(uterine artery pulsatility index[API],resistance index[RI]).Results After the intervention,the total score of TCM symptoms in the two groups was significantly lower than that before the intervention,and the total score in the observation group was lower than that in the control group(P<0.05),the total effective rate of intervention in the observation group was 95.00%,which was significantly higher than that in the control group of 65.00%(P<0.05);observation group β-The levels of EP and PGE2 were higher than those of the control group(P<0.05),PGF2α 5-HT was significantly lower than that of the control group(P<0.05),the API and RI of the observation group were lower than those of the control group,and the difference was statistically significant(P<0.05).Conclusion Jiawei Wenjing Decoction can effectively relieve the symptoms of dysmenor-rhea,regulate the endocrine environment of the uterus,reduce the level of pain medium,and improve the curative effect.It can also improve the hemodynamic indexes of the uterine artery,which is worthy of clinical application.