首页|中药联合雷公藤多苷调节紫癜性肾炎患儿凝血功能研究进展

中药联合雷公藤多苷调节紫癜性肾炎患儿凝血功能研究进展

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儿童紫癜性肾炎是儿童时期常见的继发性肾小球疾病,因其病情复杂、缠绵难愈、易于复发,往往存在预后不良的风险。此前临床上对紫癜性肾炎病因及发病机制仍存在争议,认为该病与凝血与纤溶功紊乱等因素相关,治疗上也多数采用药物联合治疗。文章就中药联合雷公藤多苷调节紫癜性肾炎患儿凝血功能相关研究、中西医治疗进展等方面进行综述,以期开拓预防和诊治的新思路。
Research Progress on Regulation of Coagulation Function in Children with Purpura Nephritis by Chinese Medicine Combined with Tripterygium Glycosides
Henoch-Schönlein purpura nephritis(HSPN)is a secondary secondary glomerular disease in children,which is often associated with poor prognosis due to its complexity,intractability and ease of recurrence.Previously,the etiology and patho-genesis of HSPN were still controversial,and it was believed that the disease was related to factors such as coagulation and fibrino-lytic mechanisms,most of the treatment used were drug combination therapy.This article reviewed the research related to the reg-ulation of coagulation function in children with HSPN by traditional Chinese medicine combined with tripterygium glycosides as well as the treatment progress in traditional Chinese and Western medicine,with a view to developing new ideas for prevention and diagnosis and treatment.

purpura nephritistripterygium glycosidescoagulation mechanismtreatmentreview

王已心、张君

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辽宁中医药大学,辽宁沈阳 110847

辽宁中医药大学附属医院,辽宁沈阳 110032

紫癜性肾炎 雷公藤多苷 凝血机制 治疗 综述

国家中医药行业专项研究项目

201507001-03

2024

实用中医内科杂志
辽宁省中医药学会,中华中医药学会,辽宁省中医药研究院

实用中医内科杂志

影响因子:0.421
ISSN:1671-7813
年,卷(期):2024.38(2)
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