中药联合雷公藤多苷调节紫癜性肾炎患儿凝血功能研究进展
Research Progress on Regulation of Coagulation Function in Children with Purpura Nephritis by Chinese Medicine Combined with Tripterygium Glycosides
王已心 1张君2
作者信息
- 1. 辽宁中医药大学,辽宁沈阳 110847
- 2. 辽宁中医药大学附属医院,辽宁沈阳 110032
- 折叠
摘要
儿童紫癜性肾炎是儿童时期常见的继发性肾小球疾病,因其病情复杂、缠绵难愈、易于复发,往往存在预后不良的风险.此前临床上对紫癜性肾炎病因及发病机制仍存在争议,认为该病与凝血与纤溶功紊乱等因素相关,治疗上也多数采用药物联合治疗.文章就中药联合雷公藤多苷调节紫癜性肾炎患儿凝血功能相关研究、中西医治疗进展等方面进行综述,以期开拓预防和诊治的新思路.
Abstract
Henoch-Schönlein purpura nephritis(HSPN)is a secondary secondary glomerular disease in children,which is often associated with poor prognosis due to its complexity,intractability and ease of recurrence.Previously,the etiology and patho-genesis of HSPN were still controversial,and it was believed that the disease was related to factors such as coagulation and fibrino-lytic mechanisms,most of the treatment used were drug combination therapy.This article reviewed the research related to the reg-ulation of coagulation function in children with HSPN by traditional Chinese medicine combined with tripterygium glycosides as well as the treatment progress in traditional Chinese and Western medicine,with a view to developing new ideas for prevention and diagnosis and treatment.
关键词
紫癜性肾炎/雷公藤多苷/凝血机制/治疗/综述Key words
purpura nephritis/tripterygium glycosides/coagulation mechanism/treatment/review引用本文复制引用
基金项目
国家中医药行业专项研究项目(201507001-03)
出版年
2024
国家科技期刊平台
NSTL
万方数据