Clinical Application and Efficacy of Traditional Chinese and Western Medicine in Treating Chronic Kidney Disease Based on the Theory of Gut-kidney Axis
Chronic kidney disease(CKD)is a social public problem that plagues the world.The prevalence of CKD in China is also increasing year by year.As CKD progresses to end-stage renal disease(ESRD),it will bring heavy economic pressure and psychological burden to CKD patients and their families.Therefore,it is urgent to delay the progressive decline of renal func-tion.At the 2011 International Dialysis Conference,Meijers et al.proposed the concept of"gut-kidney axis",believing that by regulating the intestinal flora,the production of intestinal endotoxin can be reduced,and the intestinal mucosal barrier function can be improved,thereby improving renal function.Traditional Chinese medicine has the characteristics of individualized diagnosis and treatment of dialectical treatment.Therefore,the application of traditional Chinese medicine in the treatment of CKD based on the theory of"gut-kidney axis"has considerable prospects.CKD can be attributed to"edema","uroschesis","guange"and other categories in traditional Chinese medicine.The basic pathogenesis is spleen and kidney qi deficiency,dampness and turbidity.Spleen and kidney deficiency,water metabolism disorders,"dampness","blood stasis"intrinsic intestinal,accumulation of turbid-ity toxin in the body can not be discharged in time,further aggravating kidney damage.The intestine-kidney axis is an indispen-sable part of its pathogenesis.Therefore,the treatment of CKD with the method of tonifying spleen and kidney,dredging fu-or-gans and discharging turbidity has a theoretical basis.The use of traditional Chinese medicine retention enema therapy has a-chieved good results.In recent years,with the deepening of research,the theory of"spleen-gut-kidney axis"and"lung-gut-kidney axis"has provided a theoretical basis for"treating kidney from spleen"and"treating kidney from lung",which has ex-panded a new direction for the clinical treatment of CKD with traditional Chinese medicine.The purpose of this paper is to explore the theoretical basis,clinical application and efficacy of traditional Chinese and Western medicine in the treatment of CKD based on the theory of"intestinal-kidney axis",and to provide new theoretical basis and new thinking for clinical treatment of CKD.
chronic kidney diseasegut-kidney axisprobioticstraditional Chinese medicine
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