基于"肾藏精主水"理论探析慢性心衰与水通道蛋白的相关性
Exploring the Correlation Between Chronic Heart Failure and Aquaporins Based on the Theory of"Kidney Storing Essence and Regulating Water"
何晓腾 1张艳 2张伟 1刘翔宇 1郭长余1
作者信息
- 1. 辽宁中医药大学,辽宁沈阳 110847
- 2. 辽宁中医药大学附属医院,辽宁,沈阳 110032
- 折叠
摘要
慢性心力衰竭(chronic heart failure,CHF)作为临床上各种心脏疾病发展的终末阶段,水液代谢障碍是其主要临床表现之一,因此中医常将其归为"心水""水肿"等病症范畴进行探讨及诊疗."肾藏精主水"之理论,源流于黄帝内经,是中医学用来阐释人体水液输布之大宗大本的理论依据.AQPs是一种跨膜水转运蛋白,其主要功能在于控制调节机体的水液代谢平衡,通过对其在机体之分布与功能的研究,可以发现其与"肾主水"的一些理论内涵不谋而合.文章探究中医从"肾藏精主水"理论出发论治慢性心力衰竭与AQPs的相关性.
Abstract
Chronic heart failure(CHF)is the final stage of the development of various heart diseases in clinic,and the dis-order of fluid metabolism is one of its main clinical manifestations.Therefore,traditional Chinese medicine often classifies CHF as"cardiac fluid""edema"and other diseases for argumentation,discussion and treatment.The theory of"kidney storing es-sence and controlling water"originates from the Yellow Emperor's internal meridian,and is the theoretical basis for traditional medicine to explain the bulk of the human body's water distribution.AQPs is a transmembrane water transport protein,whose main function is to control and regulate the balance of water and fluid metabolism in the body.Through the study of its distribu-tion and function in the body,we can find that it coincides with some theoretical connotation of"kidney governs water".There-fore,this article intends to explore the relationship between chronic heart failure and AQPs based on the theory of"kidney stores essence and water".
关键词
慢性心衰/肾藏精主水/水通道蛋白/心水/水肿Key words
chronic heart failure/kidney stores essence and controls water/aquaporin/heartwater disease/edema引用本文复制引用
基金项目
国家自然科学基金面上项目(82174241)
出版年
2024
国家科技期刊平台
NSTL
万方数据