首页|基于"肾藏精主水"理论探析慢性心衰与水通道蛋白的相关性

基于"肾藏精主水"理论探析慢性心衰与水通道蛋白的相关性

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慢性心力衰竭(chronic heart failure,CHF)作为临床上各种心脏疾病发展的终末阶段,水液代谢障碍是其主要临床表现之一,因此中医常将其归为"心水""水肿"等病症范畴进行探讨及诊疗。"肾藏精主水"之理论,源流于黄帝内经,是中医学用来阐释人体水液输布之大宗大本的理论依据。AQPs是一种跨膜水转运蛋白,其主要功能在于控制调节机体的水液代谢平衡,通过对其在机体之分布与功能的研究,可以发现其与"肾主水"的一些理论内涵不谋而合。文章探究中医从"肾藏精主水"理论出发论治慢性心力衰竭与AQPs的相关性。
Exploring the Correlation Between Chronic Heart Failure and Aquaporins Based on the Theory of"Kidney Storing Essence and Regulating Water"
Chronic heart failure(CHF)is the final stage of the development of various heart diseases in clinic,and the dis-order of fluid metabolism is one of its main clinical manifestations.Therefore,traditional Chinese medicine often classifies CHF as"cardiac fluid""edema"and other diseases for argumentation,discussion and treatment.The theory of"kidney storing es-sence and controlling water"originates from the Yellow Emperor's internal meridian,and is the theoretical basis for traditional medicine to explain the bulk of the human body's water distribution.AQPs is a transmembrane water transport protein,whose main function is to control and regulate the balance of water and fluid metabolism in the body.Through the study of its distribu-tion and function in the body,we can find that it coincides with some theoretical connotation of"kidney governs water".There-fore,this article intends to explore the relationship between chronic heart failure and AQPs based on the theory of"kidney stores essence and water".

chronic heart failurekidney stores essence and controls wateraquaporinheartwater diseaseedema

何晓腾、张艳、张伟、刘翔宇、郭长余

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辽宁中医药大学,辽宁沈阳 110847

辽宁中医药大学附属医院,辽宁,沈阳 110032

慢性心衰 肾藏精主水 水通道蛋白 心水 水肿

国家自然科学基金面上项目

82174241

2024

实用中医内科杂志
辽宁省中医药学会,中华中医药学会,辽宁省中医药研究院

实用中医内科杂志

影响因子:0.421
ISSN:1671-7813
年,卷(期):2024.38(3)
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