Progress in the Study of the Modulating Effect of Traditional Chinese Medicine on Bone Destruction in Rheumatoid Arthritis
Rheumatoid arthritis is characterized by synovitis and pannus formation as the basic pathological changes,The patient's main clinical presentation is dominated by multiple,symmetrical polyarticular invasive inflammation,with damage to cartilage and bone tissue occurring in the middle and later stages,ultimately leading to joint deformity and limited movement.Bone destruction occurs in the early stages of RA disease and progresses gradually throughout the course of the disease,and is one of the major factors in RA disability.Chinese medicine believes that RA bone destruction belongs to the category of"bone bi-disease"and"Wang bi",etc.,and Traditional Chinese Medicine(TCM)has achieved good efficacy in the treatment of RA.Modern experiments and clinical studies have shown that many classical prescription,proved recipe and herbal monomers can im-prove patients'conditions by effectively inhibiting synovial inflammation in RA joints and delaying bone destruction.The article collects and organizes the literature on the treatment of RA with TCM in recent years by searching relevant literature databases,and systematically analyzes the progress of research related to the inhibition of RA bone destruction by TCM,so as to provide evi-dence-based medical evidence for the treatment of RA with TCM.
Rheumatoid arthritisbone destructionTraditional Chinese Medicinepyroptosisreview
NETL
NSTL
万方数据
