Frailty is an age-related disease that is more common in the elderly.The onset of the disease is influenced by several physical,psychological and social factors.Frailty is followed by a variety of adverse outcomes,with increased hospitaliza-tion and mortality of the patients.From traditional Chinese and western medicine,this paper summarized the diagnosis,pathogen-esis and related markers of western medicine,etiology,pathogenesis and intervention measures of traditional Chinese medicine,in order to provide some reference for the study of frailty in the future.