基于血管新生机制探讨缺血性中风
Exploring Ischemic Stroke Based on Mechanism of Angiogenesis
朱娜 1马贤德 2刘树权3
作者信息
- 1. 辽宁中医药大学,辽宁沈阳 110847
- 2. 辽宁中医药大学教学实验中心,辽宁沈阳 110031
- 3. 沈阳市第二中医医院,辽宁沈阳 110101
- 折叠
摘要
中风病又称卒中,其中缺血性中风约占所有中风患者的80％.当向大脑供应富氧血液的动脉阻塞并且氧气无法到达大脑组织时,就会发生缺血性中风.血管新生有助于侧支循环的建立,在缺血性脑卒中损伤的恢复中起着关键作用,故缺血性卒中发生后,如何减轻缺血损伤及促进缺血区域血管生成,及时恢复大脑供血成为治疗的研究热点.文章综述了与缺血性中风血管生成相关的调控因子,以及促血管生成的中医药的种类和作用机制,为血管新生途径治疗缺血性中风提供理论基础.
Abstract
Stroke is also known as apoplexy,of which ischemic stroke accounts for about 80％of all stroke patients.Ischemic stroke occurs when the arteries supplying oxygen-rich blood to the brain are blocked and oxygen does not reach the brain tissue.Therefore,after the occurrence of ischemic stroke,it has become a hot research topic to reduce the ischemic damage and promote the angiogenesis of the ischemic area to restore the blood supply to the brain in time.This paper reviewed the regulatory factors associated with ischemic stroke angiogenesis,as well as the types and mechanisms of action of pro-angiogenic Chinese medicine,and provided a theoretical basis for the treatment of ischemic stroke by the angiogenesis route.
关键词
缺血性中风/血管生成/调控因子/中医药Key words
ischemic stroke/angiogenesis/regulating factors/Chinese medicine引用本文复制引用
基金项目
辽宁省自然科学基金(2019-ZD-0937)
出版年
2024
国家科技期刊平台
NSTL
万方数据