首页|基于肠肝轴理念探讨"凡十一脏取决于胆"与2型糖尿病关系

基于肠肝轴理念探讨"凡十一脏取决于胆"与2型糖尿病关系

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中医认为"凡十一脏取决于胆",胆在消渴发生发展中起重要作用,主要通过:①胆主决断,调控人体精神活动;②和解少阳枢机;③主少阳春升之气;这三个环节调控人体的新陈代谢。若枢机失常,气血不畅,则气滞、痰凝、血瘀产生,进而发为消渴。现代医学发现"肠-肝轴"与2型糖尿病发病密切相关,其内在机制可能与肠道机械屏障破坏通透性增加、化学屏障不足代谢失常、生物屏障失调能量紊乱等因素相关。因此,从"胆"出发辨证论治,结合"肠-肝轴"功能特点,为2型糖尿病的治疗提供了 一个新视角。
Exploring the Theory that"All 11 Zang-organs Dominated by Gallbladder"Based on the Intestinal-liver Axis association with Type 2 Diabetes
Traditional Chinese medcine believes that"All 11 Zang-organs are dominated by gallbladder".The gallbladder plays an important role in the occurrence and development of diabetes,mainly about:the gallbladder masters the mental activities of the human body.The gallbladder is the key point to the reconciliation of the exercise of qi.The gallbladder produces a rising qi of Shaoyang,these three links regulate the metabolism of the human body.If the qi movement is not in order,the qi stagnation,phlegm coagulation,and blood stasis are produced,and then Xiaoke happens.Modern medicine has found that the"intestinal-liver axis"is closely related to the development of type 2 diabetes mellitus and its internal mechanism may be related to the de-struction of the intestinal mechanical barrier and the increase of permeability,the lack of chemical barrier and metabolic disor-ders,biological barrier disorders,energy disorders,and other factors.Therefore,the dialectical treatment from the"gallbladder",combined with the functional characteristics of the"intestinal-liver axis",provides a new perspective for treating type 2 diabetes mellitus.

type 2 diabetes mellitusintestinal-liver axisall 11 Zang-organs dominated by gallbladdertheoretical dis-cussion

曾施琪、陈文辉、李双蕾、蒋云霞、白蕊、金鑫艳、王婷、郑洪香、贾洪洋

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广西中医药大学,广西南宁 530001

广西中医药大学第一附属医院,广西南宁 530023

广西中医药大学赛恩斯新医药学院,广西南宁 530222

2型糖尿病 肠肝轴 凡十一脏取决于胆 理论探讨

2024

实用中医内科杂志
辽宁省中医药学会,中华中医药学会,辽宁省中医药研究院

实用中医内科杂志

影响因子:0.421
ISSN:1671-7813
年,卷(期):2024.38(5)