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中医药治疗特发性肺纤维化研究进展

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特发性肺纤维化(idiopathic pulmonary fibrosis,IPF)是一种病因不明的慢性进展性、迁延性、难治性肺疾病,病死率高且治疗手段有限。中医的不断发展为IPF患者症状的缓解与生存质量的提高带来了福音。文章对IPF的中医病名、病机、中医药治疗进行了综述,并从抗炎、抗氧化应激、抗血管新生、自噬、抗上皮间质转化、抗衰老、抗内质网应激等方面对中医药治疗IPF的作用机制进行分析。
Research Progress in the Treatment of Idiopathic Pulmonary Fibrosis with Traditional Chinese Medicine
Idiopathic pulmonary fibrosis(IPF)is a chronic progressive,persistent and refractory pulmonary disease of un-known etiology,with high mortality and limited treatment.The continuous development of traditional Chinese medicine has brought good news for the relief of symptoms and improvement of quality of life of IPF patients.This article reviews the name,pathogenesis and treatment of IPF in traditional Chinese medicine,and analyzes the mechanism of the treatment of IPF by tradi-tional Chinese medicine from the aspects of anti-inflammatory,anti-oxidative stress,anti-angiogenesis,autophagy,anti-epithelial-mesenchymal transformation,anti-aging,anti-endoplasmic reticulum stress,etc.

idiopathic pulmonary fibrosislung arthralgialung flacciditytraditional Chinese medicineaction mechanism

王怡然、张文静、张伟

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山东中医药大学,山东济南 250000

山东中医药大学附属医院,山东济南 250000

特发性肺纤维化 肺痹 肺痿 中医药 作用机制

2024

实用中医内科杂志
辽宁省中医药学会,中华中医药学会,辽宁省中医药研究院

实用中医内科杂志

影响因子:0.421
ISSN:1671-7813
年,卷(期):2024.38(5)