Research Progress of Integrated Chinese and Western Medicine in Treating Primary Dysmenorrhea Based on MPAK/ERK/NF-κB Signaling Pathway
Dysmenorrhea is a common clinical gynecological disease,also known as"abdominal pain during menstruation"in Chinese medicine.It refers to spasmodic pain in the lower abdomen before and after menstruation or during menstruation,which can also radiate to the lumbosacrum,with or without nausea,vomiting,diarrhea,dizziness and weakness and other systemic symp-toms.Dysmenorrhea can be divided into two categories:primary dysmenorrhea and secondary dysmenorrhea.Secondary dysmen-orrhea is caused by organic diseases of the pelvis,such as endometriosis,adenomyosis,uterine fibroids,pelvic inflammatory dis-ease or cervical stenosis.At present,western medicine treats primary dysmenorrhea mostly with drugs to relieve spasm and pain,although the curative effect is obvious and rapid,but the side effect is large,easy to relapse after stopping the drug;the Chinese medicine in the clinical four diagnosis of combination,syndrome differentiation of treatment,not only specimens can be treated to-gether,but also help to prevent and regulate.Based on MAPK/ERK/NF-κB signaling pathway,this paper analyzed the research progress of traditional Chinese and western medicine on primary dysmenorrhea in recent 10 years,and provided theoretical basis for traditional Chinese medicine prevention and treatment of primary dysmenorrhea.The current research status of primary dys-menorrhea is summarized as follows.
primary dysmenorrheaMAPK/ERK/NF-κB signaling pathwaywestern medicine treatmenttraditional Chi-nese medicine therapy
万方数据
维普
