首页|针刺联合氟哌啶醇治疗对儿童多发性抽搐症的效果分析

针刺联合氟哌啶醇治疗对儿童多发性抽搐症的效果分析

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目的 探究针刺联合氟哌啶醇治疗儿童多发性抽搐症的临床疗效.方法 将92例多发性抽搐症患儿按照随机数字表法分为试验组和对照组各46例,对照组予以氟哌啶醇治疗,试验组在氟哌啶醇基础上加用针刺治疗,两组均连续治疗4周.比较两组治疗前后耶鲁综合抽动严重程度量表(YGTSS)、多巴胺(DA)、5-羟色胺(5-HT),治疗后临床疗效及治疗过程中不良反应.结果 治疗后,两组YGTSS评分、DA、5-HT均降低(P<0.05),试验组均低于对照组(P<0.05);治疗后,试验组临床总有效率高于对照组(P<0.05),不良反应组间比较,差异无统计学意义(P>0.05).结论 针刺联合氟哌啶醇治疗儿童多发性抽搐症可提高临床总有效率,改善临床症状,降低DA、5-HT等神经递质,治疗安全性较高.
Effect of Acupuncture Combined with Haloperidol on Children with Multiple Convulsions
Objective To explore the clinical effect of acupuncture combined with haloperidol on children with multiple convul-sions.Methods 92 children with multiple convulsions were randomly divided into test group and control group with 46.The con-trol group was treated with haloperidol,and the test group was treated with acupuncture on this basis.Both groups were treated continuously for 4 weeks.The clinical efficacy and adverse reactions of the two groups were compared before and after treatment with the Yale Comprehensive Tetch Severity Scale(YGTSS),dopamine(DA)and serotonin(5-HT).Result After treatment,YGTSS score,DA,5-HT in the two groups were decreased(P<0.05),and those in the test group were lower than those in the control group(P<0.05),after treatment,the total clinical effective rate of the test group was higher(P<0.05),and there was no significant difference between the adverse reaction groups(P>0.05).Conclusion Acupuncture combined with haloperi-dol tablets can improve the clinical total effective rate,improve the clinical symptoms,reduce DA,5-HT and other neurotrans-mitters in children with multiple convulsions,and has a high therapeutic safety.

multiple tic disease in childrenacupuncturehaloperidolyale comprehensive tic severity scaledopamine5-hydroxy tryptamine

王丹、彭伟

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湖北文理学院附属谷城医院,湖北谷城 441700

襄阳市中医医院,湖北襄阳 441000

儿童多发性抽搐症 针刺 氟哌啶醇 耶鲁综合抽动严重程度量表 多巴胺 5-羟色胺

2024

实用中医内科杂志
辽宁省中医药学会,中华中医药学会,辽宁省中医药研究院

实用中医内科杂志

影响因子:0.421
ISSN:1671-7813
年,卷(期):2024.38(5)