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通窍活血汤治疗脑梗死的临床观察

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目的 探讨通窍活血汤在脑梗死患者中的应用效果.方法 选取2021年1月-2022年12月南阳医学高等专科学校第一附属医院收治的100例脑梗死患者,根据治疗方案不同分为观察组(50例)与对照组(50例).对照组给予吸氧、抗感染、调脂等临床常规对症治疗,观察组在对照组基础上添加通窍活血汤治疗.比较两组治疗前后神经功能、肢体运动功能、中医症状总积分、生活质量、血清指标(纤维蛋白原、S100B蛋白)及治疗后临床效果.结果 治疗后,观察组NIHSS评分、中医证候积分均低于对照组(P<0.05),FMA评分、BI评分均高于对照组(P<0.05);观察组纤维蛋白原、S100B蛋白水平均低于对照组(P<0.05),观察组疗效总有效率94.00%高于对照组的80.00%(P<0.05).结论 通窍活血汤治疗脑梗死临床效果显著,能有效改善神经功能、肢体运动功能、脑组织血流状态及临床症状,提升生活质量.
Clinical Efficacy of Tongqiao Huoxue Decoction(通窍活血汤)for Cerebral Infarction
Objective To discuss the clinical efficacy of Tongqiao Huoxue Decoction(通窍活血汤)for cerebral infarction.Methods One hundred patients with cerebral infarction in First Affiliated Hospital of Nanyang Medical College from January 2021 to December 2022 were enrolled,and classified into two groups according to different treatment methods,each with 50 cases.Con-trol group received symptomatic treatment such as oxygenation,anti-infection and lipid regulation,based on this,observation group received Tongqiao Huoxue decoction.Then the National Institutes of Health Stroke Scale(NIHSS),Fugl-Meyer Assess-ment(FMA)score,Traditional Chinese medicine syndrome score,Barthel Index(BI),serum parameters(fibrinogen,S100B pro-tein)and clinical effect were compared between two groups.Results After treatment,observation group scored lower on NIHSS score and Traditional Chinese medicine syndrome scores(P<0.05),and higher on FMA and BI scores(P<0.05).Serum lev-els of fibrinogen and S100B protein were lower in observation group than in control group(P<0.05).The total efficacy rate was 94.00%in observation group,which was higher than 80.00%in control group(P<0.05).Conclusion Application of Tongqiao Huoxue decoction for cerebral infarction can effectively ameliorate the neurological function,limb motor function,brain tissue blood flow status and clinical symptoms,thus improving the quality of life of patients,which is worthy of promotion.

cerebral infarctionTongqiao Huoxue Decoction(通窍活血汤)neurological functionclinical efficacy

冯亚男、刘旻、马金玉

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南阳医学高等专科学校第一附属医院,河南南阳 473000

脑梗死 通窍活血汤 神经功能 临床效果

2024

实用中医内科杂志
辽宁省中医药学会,中华中医药学会,辽宁省中医药研究院

实用中医内科杂志

影响因子:0.421
ISSN:1671-7813
年,卷(期):2024.38(5)