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溃疡性结肠炎的发病机制及中医药干预进展

Pathogenesis of Ulcerative Colitis and Progress of Traditional Chinese Medicine Intervention

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溃疡性结肠炎(UC)是一种病因不明且易复发的慢性肠道炎症性疾病,其发病机制尚不明确,大多认为是多种因素相互作用的结果.UC的发病率逐年升高,且病情易反复,迁延难愈,是消化系统的常见疾病.中医药干预主要包括中药口服、中药灌肠、针灸、耳针、埋线等.该文主要从肠道微生物群失衡、免疫反应异常、肠黏膜屏障功能障碍、感染、遗传等方面总结了溃疡性结肠炎的发病机制及中医药干预进展,为溃疡性结肠炎的诊断、治疗及预防提供新的思路和方法.
Ulcerative colitis(UC)is a chronic intestinal inflammatory disease with unknown etiology and easy recurrence.Its pathogenesis is still unclear and most people believe that it is the result of interaction of multiple factors.The incidence of UC is increasing year by year and the disease is prone to recurrence and difficult to cure,which is a common disease of the digestive system.Traditional Chinese medicine intervention mainly includes oral administration of traditional Chinese medicine,enema of traditional Chinese medicine,acupuncture and moxbustion,ear acupuncture,thread embedding,etc.This paper summarized the pathogenesis of UC and the progress of traditional Chinese medicine intervention from the aspects of intestinal microbiome imbal-ance,abnormal immune response,intestinal mucosal barrier dysfunction,infection,genetics,etc.It provided new ideas and meth-ods for the diagnosis,treatment and prevention of UC.

ulcerative colitispathogenesistreatmenttraditional Chinese medicine intervention

张玉洁、刘兴山

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山东中医药大学第一临床医学院,山东济南 250355

潍坊市中医院,山东潍坊 261041

溃疡性结肠炎 发病机制 治疗 中医药干预

潍坊市卫生健康委中医药科研项目(第一类)(2022)

第WFZYY2022-1-001号

2024

实用中医内科杂志
辽宁省中医药学会,中华中医药学会,辽宁省中医药研究院

实用中医内科杂志

影响因子:0.421
ISSN:1671-7813
年,卷(期):2024.38(6)
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