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针刺治疗偏头痛的机制研究进展

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偏头痛是一种常见的失能性原发性头痛,严重影响患者的工作及生活。针刺对偏头痛预防性治疗及急性期治疗在临床上被证实确有疗效,诸多学者通过临床研究及动物实验对针刺治疗偏头痛的机制进行了不同角度的探索。得出针刺主要是调节三叉神经血管通路相关物质水平、改善脑血管血流速度、抑制c-fos基因及蛋白水平表、调节脑功能网络的异常连接等作用起到治疗偏头痛的结论。
Research Progress on Mechanism of Acupuncture Treatment for Migraine
Migraine is a common incapacitated primary headache,which seriously affects the patient's work and life.Acu-puncture has been clinically proven to be effective in the preventive treatment and acute phase treatment of migraine.Many schol-ars have explored the mechanism of acupuncture in the treatment of migraine from different angles through clinical studies and an-imal experiments.It is concluded that acupuncture can regulate the levels of trigeminal vascular pathway related substances,im-prove cerebral blood flow velocity,inhibit c-fos gene and protein level and regulate the abnormal connection of brain functional network to treat migraine.

migraineacupuncture5-HT and its receptorCGRPSPNOc-fos gene and proteincerebrovascular blood flow velocity

黄雅帝、何婷婷、陈雯雯、刘永辉

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广西中医药大学,广西南宁 530001

广西中医药大学第一附属医院,广西南宁 530023

偏头痛 针刺 5-HT及其受体 CGRP SP NO c-fos基因及蛋白 脑血管血流速度

2024

实用中医内科杂志
辽宁省中医药学会,中华中医药学会,辽宁省中医药研究院

实用中医内科杂志

影响因子:0.421
ISSN:1671-7813
年,卷(期):2024.38(8)