Overview of Mechanism of TCM Prevention and Treatment of Liver Cancer
The etiology and pathogenesis of liver cancer are complex and intricate.Traditional Chinese medicine believes that the basic prerequisite for the onset of liver cancer is the deficiency of righteous Qi.If the Qi deficiency occurs,the internal and external evils can attack the body,causing dysfunction of Zang-Fu organs,loss of controlling Qi,blood and body fluids.The ac-cumulation of phlegm,dampness,heat,blood stasis and toxins inside cannot disperse,leading to liver cancer over time.According to the different pathogenesis of liver cancer,there are also differences in its treatment methods.The long-term use of Western medicine not only leads to a decrease in sensitivity to chemotherapy drugs,but also leads to drug resistance and large adverse re-actions,which are often difficult to bear.Traditional Chinese medicine,with its holistic concept,syndrome differentiation and treatment characteristics,combined with the three factors tailored treatment concept,has obvious advantages in the treatment of liver cancer,and can significantly improve the clinical efficacy,reduce patients'physical and mental pain,improve the quality of life and prolong the survival.In recent years,the research on the mechanism of traditional Chinese medicine in preventing and treating liver cancer has gradually deepened and made significant progress,mainly focusing on inhibiting cancer cell proliferation,blocking cell cycle,inducing cancer cell suicide and autophagy,enhancing immune function,regulating signaling pathways and re-versing drug resistance in liver cancer cells.This article provided a brief review of the research progress on the mechanism of ac-tion of traditional Chinese medicine in the prevention and treatment of liver cancer,as well as the scientific ideas and basis for fu-ture research on the mechanism of action of traditional Chinese medicine in the prevention and treatment of liver cancer and its clinical rational application.
traditional Chinese medicinemechanism of actionliver cancercell proliferationsignaling pathway