实用中医内科杂志2024,Vol.38Issue(8) :76-79.DOI:10.13729/j.issn.1671-7813.Z20231768

基于肠道菌群介导脑肠轴理论探讨中医药调节艾滋病相关性腹泻的作用机制

Based on the Theory of Intestinal Flora Mediating Brain-Gut Axis,the Mechanism of TCM Regulating AIDS-Related Diarrhea was Investigated

苏生勤 刘振威 曹丽 翁晓新 胡玥晗 李爽
实用中医内科杂志2024,Vol.38Issue(8) :76-79.DOI:10.13729/j.issn.1671-7813.Z20231768

基于肠道菌群介导脑肠轴理论探讨中医药调节艾滋病相关性腹泻的作用机制

Based on the Theory of Intestinal Flora Mediating Brain-Gut Axis,the Mechanism of TCM Regulating AIDS-Related Diarrhea was Investigated

苏生勤 1刘振威 2曹丽 1翁晓新 1胡玥晗 1李爽1
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作者信息

  • 1. 广西中医药大学,广西南宁 530001
  • 2. 广西中医药大学附属瑞康医院,广西南宁 530011
  • 折叠

摘要

艾滋病(Human immunodeficiency virus,HIV)相关性腹泻与人体的肠道免疫功能以及肠道菌群的活动有着重要关联.脑肠轴是复杂的神经-内分泌网络,能双向调节脑与胃肠道,肠道菌群是脑肠轴的通路之一.此外研究发现,人体肠道菌群会随着肠道免疫状态的变化而变化,且也会受到神经系统的重要影响,而神经系统亦可反向调节肠道微生态的平衡.通过中医药治疗艾滋病相关性腹泻已有论述,但基于肠道菌群介导脑肠轴理论中医药调节HIV相关性腹泻是否存在相关性研究较少.因此深入研究基于肠道菌群介导脑肠轴理论的中医治疗,将为艾滋病相关性腹泻在临床防治提供新的治疗方法.

Abstract

HIV related diarrhea is closely related to the human intestinal immune function and the activity of gut microbiota.The brain gut axis is a complex neuroendocrine network that can regulate the brain and gastrointestinal tract in both directions.The gut microbiota is one of the pathways of the brain gut axis.In addition,research has found that the gut microbiota of the hu-man body changes with changes in the intestinal immune status and is also significantly influenced by the nervous system,which can reverse regulate the balance of gut microbiota.The treatment of AIDS related diarrhea by traditional Chinese medicine has been discussed,but there is less research on whether there is correlation between TCM and HIV related diarrhea based on the theory of intestinal flora mediated brain gut axis.Therefore,in-depth study of TCM treatment based on the theory of intestinal flora mediated brain gut axis will provide a new treatment method for AIDS related diarrhea in clinical prevention and treatment.

关键词

中医药/脑肠轴/肠道菌群/艾滋病相关性腹泻

Key words

Traditional Chinese medicine/Cerebrointestinal axis/Intestinal flora/Aids-related diarrhea

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出版年

2024
实用中医内科杂志
辽宁省中医药学会,中华中医药学会,辽宁省中医药研究院

实用中医内科杂志

影响因子:0.421
ISSN:1671-7813
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