Research Progress in Treatment of Functional Constipation by Regulating Gastrointestinal Hormone Levels with Traditional Chinese Medicine
Functional constipation(FC)is a disease that requires the elimination of bowel and systemic organic factors,drugs and other causes of constipation.An constipation is characterized by abdominal pain,dry stools,difficulty defecating,reduced fre-quency of bowel movements or a sense of incomplete bowel movements.The pathological mechanism of this disease is complex,which is caused by many reasons.Among them,the abnormal level of gastrointestinal hormone is an important pathological feature of FC,which is a popular direction in the current research of digestive system diseases.Gastrointestinal hormones are a variety of small molecule active peptides released by gastrointestinal endocrine cells and nerve cells,also known as gastrointestinal pep-tides,more than 40 kinds of gastrointestinal hormones have been discovered and identified by the medical community.Nowadays,domestic and foreign studies have shown that gastrointestinal hormones have obvious regulatory effects on FC,which has greatly promoted the development of digestive system.Ancestral medicine has rich experience in the treatment of FC,and a large number of studies have shown that traditional Chinese medicine can effectively block the occurrence and development of FC through multi-target and multi-channel regulation of gastrointestinal hormones,so as to effectively treat FC.Therefore,this article made the review from the perspective of TCM regulation of gastrointestinal hormone levels in the treatment of FC.
functional constipationgastrointestinal hormonetraditional Chinese medicineaction mechanism