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卒中后抑郁的发病机制及非药物疗法临床研究进展

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卒中后抑郁(PSD)是脑卒中常见并发症之一,发病机制复杂,影响脑卒中幸存者的治疗效果及预后,成为广受关注的公众健康问题.目前临床应用药物治疗卒中后抑郁的有效性和安全性存在争议,且患者依从性差,临床效果并不理想.目前非药物疗法作为一种安全、有效的临床治疗方法,已广泛用于不耐受、拒绝药物治疗或药物治疗效果不理想的PSD患者.文章围绕卒中后抑郁的发病机制进行探讨,并对非药物疗法的临床研究进展进行综述.
Clinical Research Progress on Pathogenesis of Post-Stroke Depression and Non-Pharmacological Therapies
Post-stroke depression(PSD)is one of the common complications of stroke,and the pathogenesis is complex,affecting the treatment effect and prognosis of stroke survivors,and has become a public health problem of widespread concern.At present,the efficacy and safety of clinical use of drugs for post-stroke depression are controversial,and the patient compliance is poor,and the clinical effect is not satisfactory.At present,non-drug therapy as a safe and effective clinical treatment has been widely used in pa-tients with PSD who are intolerant,refuse drug treatment or have an unsatisfactory response to drug treatment.This article discussed the pathogenesis of depression after stroke and reviewed the clinical research progress of non-drug therapies.

post-stroke depressionpathogenesisnon-pharmacological therapiesreview

宋雅婷、苏莉

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山东中医药大学,山东青岛 266000

青岛市中医医院,山东青岛 266000

卒中后抑郁 发病机制 非药物疗法 综述

2024

实用中医内科杂志
辽宁省中医药学会,中华中医药学会,辽宁省中医药研究院

实用中医内科杂志

影响因子:0.421
ISSN:1671-7813
年,卷(期):2024.38(8)