Study on Regulation of Signal Pathway Related to Irritable Bowel Syndrome by Traditional Chinese Medicine
Irritable bowel syndrome(IBS)is a common disease of intestinal functional disorder in clinic,the pathogenesis is complex and has not been very clear at present,and the incidence of IBS is increasing year by year,which seriously affects the quality of life and work efficiency of patients.The routine treatment of western medicine is mainly antispasmodic,antidiarrhea,antidepressant and so on,but the curative effect is not good and the symptoms are difficult to heal.Traditional Chinese medicine in the treatment of diseases on the basis of dialectical treatment,pay attention to the overall concept,specimen treatment.A large number of studies have shown that traditional Chinese medicine can act on signal pathway to treat IBS.Compared with west-ern medicine,traditional Chinese medicine has the advantages of multi-level,multi-link and multi-target.By consulting the literature at home and abroad,the author collates the NF-κB/AKT-STAT/TRPV1/5-HT/MAPK/MicroRNAs related signal pathway in recent years,hoping to provide a new way of thinking for the treatment of IBS with traditional Chinese medi-cine.
traditional Chinese medicineirritable bowel syndromesignal pathwayresearch progress