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从"燥邪"再论放射性心脏损伤

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放射性心脏病是患者接受放射治疗后引起的迟发性严重心血管并发症,随着放射性治疗模式的进步,放射性心脏病越来越成为影响放射性治疗幸存者生存预期和生活质量的关键临床问题,其生理病理机制目前尚未完全阐明,临床缺乏有效治疗方案。而中医药在防治辐射相关损伤方面表现出了巨大潜力,基于临床实践发现"燥邪"特性与放射性心脏病的迟发效应完全契合,燥邪侵袭,体虚而伏,损耗津液,气血亏虚,心失濡养而致心脏损伤,治疗予以益气养阴、活血通络为基本治法,在临床论治放射性心脏病取得了显著的临床疗效,因此,注重开发靶向性天然中医药产物,推动中医药临床转化是治疗放射性心脏损伤的形势所趋。
Re-Discussion on Radiation-Induced Heart Injury from"Dryness"
Radiation heart disease is a delayed serious cardiovascular complication caused by radiotherapy.With the progress of radiation therapy mode,radiation heart disease has increasingly become a key clinical problem affecting the survival expecta-tion and quality of life of radiation treatment survivors.Its physiological and pathological mechanism has not been fully elucida-ted,and there is a lack of effective clinical treatment.On the other hand,traditional Chinese medicine shows great potential in the prevention and treatment of radiation-related injury.based on clinical practice,it is found that the characteristics of"dry-ness pathogen"are completely consistent with the delayed effect of radiation heart disease,such as dryness pathogen attack,body deficiency,loss of body fluid and deficiency of qi and blood.Heart injury caused by loss of osmosis,the basic treatment is re-plenishing qi and nourishing yin,activating blood circulation and dredging collaterals,and remarkable clinical effect has been obtained in the clinical treatment of radiation heart disease.Paying attention to the development of targeted natural traditional Chinese medicine products and promoting the clinical transformation of traditional Chinese medicine is the trend of the treatment of radiation-induced heart injury.

Radiation heart diseasedryness pathogentraditional Chinese medicine

马彪、吴荣、魏科、崔玉苗、马吾生、胡启芬、何欣蓉

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甘肃中医药大学,甘肃兰州 730000

甘肃省中医药研究所,甘肃兰州 730050

放射性心脏病 燥邪 中医药

2024

实用中医内科杂志
辽宁省中医药学会,中华中医药学会,辽宁省中医药研究院

实用中医内科杂志

影响因子:0.421
ISSN:1671-7813
年,卷(期):2024.38(9)