首页|壮肝逐瘀煎调控肝脏相关信号通路研究进展

壮肝逐瘀煎调控肝脏相关信号通路研究进展

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壮肝逐瘀煎是目前广西治疗肝脏相关疾病的常用效方,近年来广泛应用于肝纤维化、肝硬化、肝癌等治疗中.该文通过对信号通路研究的检测指标及结果进行分析归纳,发现在信号通路方面有多元化,多角度的研究趋势,目前研究以转化生长因子-β1/Smads为主;25篇文献研究中,有24篇明确提及壮肝逐瘀煎具有明显的抗肝纤维化甚至是逆转肝纤维化的作用,为进一步拓宽临床使用范围提供了重要的理论基础和科学依据.
Research Progress on Regulation of Liver Related Signaling Pathways by Zhuanggan Zhuyu Decoction(壮肝逐瘀煎)
Zhuanggan Zhuyu Decoction(壮肝逐瘀煎)is a commonly used prescription for the treatment of liver-related diseases in Guangxi,and has been widely used in the treatment of liver fibrosis,cirrhosis and liver cancer in recent years.Through the analysis and summary of the detection indicators and results of the signaling pathway research,it is found that there is a diversified and multi-angle research trend in the signaling pathway,and the current research mainly focuses on transforming growth factor-β1/Smads.Among the 25 literature studies,24 articles explicitly mentioned that Zhuanggan Zhuyu Decoction had obvious anti-liver fibrosis or even reverse liver fibrosis,which provided an important theoretical basis and scientific basis for fur-ther expanding clinical use.

Zhuanggan Zhuyu Decoction(壮肝逐瘀煎)signal pathhepatitisliver fibrosisliver cirrhosis

李爽、梁尧、刘旭东、曹丽、苏生勤、翁晓新、胡玥晗、刘振威

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广西中医药大学,广西南宁 530200

广西中医药大学第一附属医院,广西南宁 530022

广西中医药大学附属瑞康医院,广西南宁 530011

壮肝逐瘀煎 信号通路 肝炎 肝纤维化 肝硬化

第七批全国老中医药专家学术经验继承项目广西中医药大学桂派中医药传承创新团队资助项目

20210072022B004

2024

实用中医内科杂志
辽宁省中医药学会,中华中医药学会,辽宁省中医药研究院

实用中医内科杂志

影响因子:0.421
ISSN:1671-7813
年,卷(期):2024.38(10)