Idiopathic pulmonary fibrosis(IPF)is a chronic progressive interstitial pneumonia with unknown etiology.The prog-nosis of patients is poor,and the mortality rate is high.At present,only pirfenidone and nidanib are used to treat IPF,but the treat-ment effect is slightly poor,and the patients cannot be completely cured.Shengjiang Powder(升降散)has the functions of clearing away turbidity,regulating Qi-flowing,promoting blood circulation and removing blood stasis,resolving phlegm and resolving stagna-tion,and clearing away heat and toxic materials,which are the key to the pathogenesis of IPF,including phlegm,blood stasis,toxin and lung.In addition,combined with the pharmacological effects of Shengjiang Powder at present,it is found that IPF can be allevia-ted or improved through multiple channels and multiple targets.This paper discussed the clinical application characteristics and pharmacological mechanism of Shengjiang Pwder in the treatment of IPF,and provided new treatment ideas for IPF patients.
关键词
升降散/IPF/病因病机/药理研究
Key words
Shengjiang Powder(升降散)/IPF/etiology and pathogenesis/pharmacological research
维普
万方数据