首页|基于JAK/STAT通路中医药治疗急性缺血性脑卒中的研究进展

基于JAK/STAT通路中医药治疗急性缺血性脑卒中的研究进展

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脑梗死是我国高发疾病,其发病机制复杂,涉及多个信号通路.JAK/STAT通路在脑梗死发病过程中的作用逐渐受到关注.中医药在脑梗死治疗中展现出独特优势,但其作用于该通路的机制尚未完全明确.文章以JAK/STAT信号通路作为切入点,对该通路进行系统概述,总结在中医药治疗缺血性脑卒中的有效成分和相关靶点,以期为中医药治疗缺血性脑卒中提供了新的思路和方法.
Advances in the Treatment of Acute Cerebral Infarction with Traditional Chinese Medicine Based on JAK/STAT pathway
Acute cerebral infarction is a highly prevalent disease in China,characterized by complex pathogenesis involving multiple signaling pathways.The role of the JAK/STAT pathway in the pathogenesis of cerebral infarction has garnered increasing attention.Traditional Chinese medicine has demonstrated unique advantages in treating cerebral infarction;however,its mecha-nism of action on this pathway remains incompletely elucidated.This paper systematically summarizes the JAK/STAT signaling pathway as a starting point and further consolidates effective components and related targets for ischemic stroke treatment using traditional Chinese medicine,aiming to provide novel ideas and approaches for traditional Chinese medicine-based management of ischemic stroke.

acute cerebral infarctionstrokeJAK/STAT pathwayTraditional Chinese medicine

顾浩平、杨洋、严年文

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福建中医药大学附属人民医院,福建 福州 350000

缺血性脑卒中 中风 JAK/STAT信号转导通路 中医药

福建省引导性科技计划项目

2023Y0032

2024

实用中医内科杂志
辽宁省中医药学会,中华中医药学会,辽宁省中医药研究院

实用中医内科杂志

影响因子:0.421
ISSN:1671-7813
年,卷(期):2024.38(10)