Acute cerebral infarction is a highly prevalent disease in China,characterized by complex pathogenesis involving multiple signaling pathways.The role of the JAK/STAT pathway in the pathogenesis of cerebral infarction has garnered increasing attention.Traditional Chinese medicine has demonstrated unique advantages in treating cerebral infarction;however,its mecha-nism of action on this pathway remains incompletely elucidated.This paper systematically summarizes the JAK/STAT signaling pathway as a starting point and further consolidates effective components and related targets for ischemic stroke treatment using traditional Chinese medicine,aiming to provide novel ideas and approaches for traditional Chinese medicine-based management of ischemic stroke.
关键词
缺血性脑卒中/中风/JAK/STAT信号转导通路/中医药
Key words
acute cerebral infarction/stroke/JAK/STAT pathway/Traditional Chinese medicine