首页|基于NF-κB信号通路探讨中医药治疗偏头痛的研究进展

基于NF-κB信号通路探讨中医药治疗偏头痛的研究进展

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偏头痛(migraine)是一种常见的慢性神经系统疾病,其发病率较高且病情具有反复性,严重影响患者的身心健康并降低其生活质量。该疾病的发病机制复杂,涉及神经、血管和炎症等多个信号通路的相互作用。中医药作为一种综合性疗法,在偏头痛治疗中展现出了独特的优势。其可以通过核因子-κB(Nuclear Factor-kappa B,NF-κB)及其他信号通路,减轻炎症、疼痛和血管异常等病理生理过程来缓解偏头痛症状,故基于NF-κB信号通路探讨中医药治疗偏头痛的发展具有重要意义。文章综述了近年来关于中医药治疗偏头痛的研究进展,重点关注了 NF-κB信号通路在偏头痛发病机制中的作用,以期为深入理解偏头痛发病机制和治疗策略提供启示。
Research Progress on Traditional Chinese Medicine for Migraine Treatment Based on Signaling Pathways
Migraine is a common chronic neurological disease with high incidence and repeatability,which seriously affects the physical and mental health of patients and reduces their quality of life.The pathogenesis of the disease is complex and in-volves the interaction of multiple signaling pathways such as nerves,blood vessels and inflammation.As a comprehensive treat-ment,traditional Chinese medicine has shown its unique advantages in the treatment of migraine.It can relieve migraine symp-toms by regulating Nuclear Factor-κB(NF-κB)and other signaling pathways,thereby reducing inflammation,pain,and vas-cular abnormalities,as well as other pathological and physiological processes.Therefore,it is of great significance to explore the development of traditional Chinese medicine for migraine treatment based on NF-κB signaling pathway.This article reviews the research progress of traditional Chinese medicine in the treatment of migraine in recent years,focusing on the role of NF-κB sig-naling pathway in the pathogenesis of migraine,in order to provide insights into the pathogenesis and treatment strategies of mi-graine.

migraineNF-κBsignaling pathwayChinese medicineresearch progress

孙亚丽、赵继业、秦瑛烁、任国华

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内蒙古医科大学,内蒙古呼和浩特 010020

内蒙古自治区中医医院,内蒙古呼和浩特 010051

偏头痛 NF-κB 信号通路 中医药 研究进展

2024

实用中医内科杂志
辽宁省中医药学会,中华中医药学会,辽宁省中医药研究院

实用中医内科杂志

影响因子:0.421
ISSN:1671-7813
年,卷(期):2024.38(12)