Research Progress on Traditional Chinese Medicine for Migraine Treatment Based on Signaling Pathways
Migraine is a common chronic neurological disease with high incidence and repeatability,which seriously affects the physical and mental health of patients and reduces their quality of life.The pathogenesis of the disease is complex and in-volves the interaction of multiple signaling pathways such as nerves,blood vessels and inflammation.As a comprehensive treat-ment,traditional Chinese medicine has shown its unique advantages in the treatment of migraine.It can relieve migraine symp-toms by regulating Nuclear Factor-κB(NF-κB)and other signaling pathways,thereby reducing inflammation,pain,and vas-cular abnormalities,as well as other pathological and physiological processes.Therefore,it is of great significance to explore the development of traditional Chinese medicine for migraine treatment based on NF-κB signaling pathway.This article reviews the research progress of traditional Chinese medicine in the treatment of migraine in recent years,focusing on the role of NF-κB sig-naling pathway in the pathogenesis of migraine,in order to provide insights into the pathogenesis and treatment strategies of mi-graine.