首页|金匮肾气丸辅治Ⅱ-Ⅲ期糖尿病肾病疗效观察

金匮肾气丸辅治Ⅱ-Ⅲ期糖尿病肾病疗效观察

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目的:观察金匮肾气丸辅治Ⅱ-Ⅲ期糖尿病肾病的临床疗效.方法:74例按照随机数字表法分为对照组与研究组各37例,两组均用达格列净和贝那普利治疗,研究组加用金匮肾气丸.结果:研究组总有效率与估算肾小球滤过率(eGFR)水平高于对照组(P<0.05),中医证候积分、血肌酐(SCR)、血尿素氮(BUN)、24h尿总量蛋白(TUP)和尿微量白蛋白/尿肌酐(UMA/UCR)以及空腹血糖(FBG)水平均低于对照组(P<0.05).结论:金匮肾气丸辅治Ⅱ-Ⅲ期糖尿病肾病可提高疗效.
Objective:To observe the clinical efficacy of Jinkui Shenqi Pill in the treatment of diabetic nephropathy of stage Ⅱ-Ⅲ.Methods:Seventy-four cases were divided into the control group and the study group according to the random number table method,37 cases in each group.Both groups were treated with dapagliflozin and benazepril and the study group were additionally treated with Jingui Shenqi Pills.Results:The total effective rate and estimated glomerular filtration rate(eGFR)in the study group were higher than those in the control group(P<0.05).The scores of TCM syndromes,serum creatinine(SCR),blood urea nitrogen(BUN),24-hour urinary total protein(TUP),urinary microalbumin/urinary creatinine(UMA/UCR)and fasting blood glucose(FBG)were lower than those in the control group(P<0.05).Conclusion:Jingui Shenqi Pill could improve the curative effect in the treatment of diabetic nephropathy of stage Ⅱ-Ⅲ.

Diabetic nephropathy of Ⅱ-Ⅲ stageJingui Shenqi PillDapagliflozinBenazepril

焦书沛、杨会杰

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河南宏力医院内分泌科,河南长垣 453400

Ⅱ-Ⅲ期糖尿病肾病 金匮肾气丸 达格列净 贝那普利

2024

实用中医药杂志
重庆医科大学中医药学院

实用中医药杂志

影响因子:0.546
ISSN:1004-2814
年,卷(期):2024.40(2)
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