Objective:To observe the clinical effect of Zhiyang Lotion in the treatment of scalp seborrheic dermatitis(SSD)of dampness-heat type.Methods:Ninety-six cases were randomly divided into treatment group and control group,48 cases in each group.The treatment group were treated with antipruritic lotion while the control group were treated with 2%ketoconazole lotion.Results:The total effective rate of the treatment group was higher than that of the control group(P<0.05).The skin lesion symptom score in the treatment group was lower than that in the control group(P<0.05).Conclusion:Zhiyang Lotion is effective in the treatment of SSD of dampness-heat type.