Objective:To observe the curative effect of Guizhi Shaoyao Zhimu Decoction combined with Tongbi Capsule on rheumatoid arthritis(RA).Methods:Seventy-eight cases were randomly divided into monotherapy group and treatment group,with 39 cases in each group.The monotherapy group were treated with Tongbi Capsule,while the treatment group were treated with Guizhi Shaoyao Zhimu Decoction combined with Tongbi Capsule.Results:The total effective rate in the treatment group was higher than that in the monotherapy group(P＜0.05).After treatment,the TCM syndrome score,HAQ and DAS28 scores in the treatment group were lower than those in the monotherapy group(P＜0.05).After treatment,the levels of IL-6,CRP and TNF-α in both groups decreased,but the decline in the treatment group was more significant(P＜0.05).After treatment,the levels of BGP and ALP in the treatment group were higher than those in the monotherapy group(P＜0.05)while the levels of RF and ESR were lower than those in the monotherapy group(P＜0.05).The levels of C3 in the treatment group were higher than those in the monotherapy group,and the levels of IgG,IgM and IgA were lower than those in the monotherapy group(P＜0.05).Conclusion:Guizhi Shaoyao Zhimu Decoction combined with Tongbi Capsule is effective in treating RA.
Rheumatoid arthritis(RA)Guizhi Shaoyao Zhimu DecoctionTongbi CapsuleControl treatment and observation
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