Objective:To observe the effect of Bushen Tongluo Decoction combined with olmesartan medoxomil in the treatment of diabetic nephropathy(DN).Methods:Eighty-two cases were randomly divided into the control group and the combined group,41 cases in each group.Both groups were treated with olmesartan medoxomil,and the combined group were treated with Bushen Tongluo Decoction.Results:The total effective rate of the combined group was higher than that of the control group(P＜0.05).After treatment,the main symptoms,secondary symptoms and total scores of TCM syndromes in the combined group were lower than those in the control group(P＜0.05).After treatment,FPG,Scr,mAlb and BUN in the combined group were lower than those before treatment(P＜0.05).After treatment,MPO and CAT decreased and SOD increased in both groups.The changes in the combined group were more significant(P＜0.05).After treatment,the increase of Treg in the combined group was greater than that in the control group(P＜0.05),while the decrease of TH1,TH 17/Treg and TH1/TH2 was greater than that in the control group(P＜0.05).Conclusion:Bushen Tongluo Decoction combined with olmesartan medoxomil is effective in the treatment of DN.
NETL
NSTL
万方数据
