Objective:To observe the effect of supplemented Xiaoxianxiong Decoction in adjuvant treatment of obese polycystic ovary syndrome(PCOS).Methods:Ninety-eight cases were randomly divided into the study group and the control group,49 cases in each group.Both groups were treated with ethinylestradiol and cyproterone acetate tablets,and the study group were treated with supplemented Xiao Xianxiong Decoction.Both groups were treated for 3 months.Results:After treatment,FPG,FINS,HOMA-IR,TG and TC decreased and HDL-C increased in both groups(P<0.05).The improvement in the study group was better than that in the control group(P<0.05).After treatment,the number of follicles in the ovary,the volume of the right ovary,the volume of the left ovary and RI decreased,while the endometrial thickness,PI and PSV increased in the two groups(P<0.05).The improvement in the study group was better than that in the control group(P<0.05).The levels of CRP,IL-6 and TNF-α in the two groups decreased after treatment,and the levels of CRP,IL-6 and TNF-αafter 3 months of treatment were lower than those after 1 month of treatment(P<0.05).The levels of CRP,IL-6 and TNF-αin the study group were lower than those in the control group after 3 months of treatment and 1 month of treatment(P<0.05).Conclusion:Supplemented Xiao Xianxiong Decoction in adjuvant treatment of obese polycystic ovary syndrome could improve the curative effect.